Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 76 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
O00264 O00264 P22102 PGRMC1 GART human ortho
O00264 O00264 P22830 PGRMC1 FECH human exp
O00264 O00264 Q92616 PGRMC1 GCN1 human exp
O00264 O00264 P11717 PGRMC1 IGF2R human pred
O00264 O00264 P20645 PGRMC1 M6PR human pred
O00264 O00264 P11441 PGRMC1 UBL4A human exp
O00264 O00264 O00264 PGRMC1 PGRMC1 human exp
O00264 O00264 O43169 PGRMC1 CYB5B human pred
O00264 O00264 P51149 PGRMC1 RAB7A human ortho
O00264 O00264 P28845 PGRMC1 HSD11B1 human ortho
O00264 O00264 P62258 PGRMC1 YWHAE human ortho
O00264 O00264 P31943 PGRMC1 HNRNPH1 human exp
O00264 O00264 O60739 PGRMC1 EIF1B human exp
O00264 O00264 Q14318 PGRMC1 FKBP8 human exp
O00264 O00264 Q13618 PGRMC1 CUL3 human exp
O00264 O00264 P28288 PGRMC1 ABCD3 human exp
O00264 O00264 P60866 PGRMC1 RPS20 human exp
O00264 O00264 P68133 PGRMC1 ACTA1 human ortho,pred
O00264 O00264 P27348 PGRMC1 YWHAQ human pred
O00264 O00264 P29372 PGRMC1 MPG human exp
O00264 O00264 P62633 PGRMC1 CNBP human ortho
O00264 O00264 Q96BA8 PGRMC1 CREB3L1 human exp
O00264 O00264 P84103 PGRMC1 SRSF3 human exp
O00264 O00264 Q9H0W5 PGRMC1 CCDC8 human exp
O00264 O00264 Q6NUS6 PGRMC1 TCTN3 human exp
O00264 O00264 P04201 PGRMC1 MAS1 human pred
O00264 O00264 Q9BUP0 PGRMC1 EFHD1 human exp
O00264 O00264 P35244 PGRMC1 RPA3 human exp
O00264 O00264 Q96FW1 PGRMC1 OTUB1 human exp
O00264 O00264 Q13177 PGRMC1 PAK2 human exp
O00264 O00264 Q86Y56 PGRMC1 - human exp
O00264 O00264 Q9H2F3 PGRMC1 HSD3B7 human ortho
O00264 O00264 P63261 PGRMC1 ACTG1 human ortho,pred
O00264 O00264 O60664 PGRMC1 PLIN3 human pred
O00264 O00264 Q8N442 PGRMC1 GUF1 human ortho
O00264 O00264 P07099 PGRMC1 EPHX1 human ortho
O00264 O00264 P15927 PGRMC1 RPA2 human exp
O00264 O00264 Q9Y3D7 PGRMC1 PAM16 human exp
O00264 O00264 P16035 PGRMC1 TIMP2 human exp
O00264 O00264 P39656 PGRMC1 DDOST human exp
O00264 O00264 Q15233 PGRMC1 NONO human pred
O00264 O00264 Q14164 PGRMC1 IKBKE human exp
O00264 O00264 Q9H1Y0 PGRMC1 ATG5 human exp
O00264 O00264 O43567 PGRMC1 RNF13 human exp
O00264 O00264 Q16850 PGRMC1 CYP51A1 human ortho,pred
O00264 O00264 Q6DD88 PGRMC1 ATL3 human exp
O00264 O00264 P27694 PGRMC1 RPA1 human exp
O00264 O00264 Q9H9B4 PGRMC1 SFXN1 human exp
O00264 O00264 P49326 PGRMC1 FMO5 human ortho
O00264 O00264 Q14999 PGRMC1 CUL7 human exp
O00264 O00264 P08684 PGRMC1 CYP3A4 human exp
O00264 O00264 P31946 PGRMC1 YWHAB human ortho,pred
O00264 O00264 P48039 PGRMC1 MTNR1A human exp
O00264 O00264 Q9ULK4 PGRMC1 MED23 human exp
O00264 O00264 Q00839 PGRMC1 HNRNPU human exp
O00264 O00264 P16435 PGRMC1 POR human exp
O00264 O00264 P07550 PGRMC1 ADRB2 human exp
O00264 O00264 Q12906 PGRMC1 ILF3 human exp
O00264 O00264 Q92905 PGRMC1 COPS5 human exp
O00264 O00264 O15503 PGRMC1 INSIG1 human exp
O00264 O00264 P40337 PGRMC1 VHL human exp
O00264 O00264 Q8NC51 PGRMC1 SERBP1 human pred
O00264 O00264 P30480 PGRMC1 HLA-B human exp
O00264 O00264 Q12770 PGRMC1 SCAP human exp
O00264 O00264 Q15005 PGRMC1 SPCS2 human exp
O00264 O00264 P10632 PGRMC1 CYP2C8 human exp
O00264 O00264 P51572 PGRMC1 BCAP31 human exp
O00264 O00264 P22392 PGRMC1 NME2 human exp
O00264 O00264 P33121 PGRMC1 ACSL1 human ortho
O00264 O00264 Q71F23 PGRMC1 CENPU human exp
O00264 O00264 P27824 PGRMC1 CANX human exp
O00264 O00264 O75832 PGRMC1 PSMD10 human pred
O00264 O00264 O14713 PGRMC1 ITGB1BP1 human exp
O00264 O00264 Q8NBP7 PGRMC1 PCSK9 human exp
O00264 O00264 Q9Y4K3 PGRMC1 TRAF6 human exp
O00264 O00264 P23508 PGRMC1 MCC human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.