Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 22 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
O00584 O00584 Q9UL18 RNASET2 AGO1 human pred
O00584 O00584 Q9NQR4 RNASET2 NIT2 human exp
O00584 O00584 Q14258 RNASET2 TRIM25 human exp
O00584 O00584 Q12933 RNASET2 TRAF2 human exp
O00584 O00584 Q13571 RNASET2 LAPTM5 human pred
O00584 O00584 P05107 RNASET2 ITGB2 human pred
O00584 O00584 Q14554 RNASET2 PDIA5 human exp
O00584 O00584 P07333 RNASET2 CSF1R human pred
O00584 O00584 P49821 RNASET2 NDUFV1 human exp
O00584 O00584 Q9UII2 RNASET2 ATPIF1 human exp
O00584 O00584 Q9NRD1 RNASET2 FBXO6 human exp
O00584 O00584 Q96I99 RNASET2 SUCLG2 human exp
O00584 O00584 O43914 RNASET2 TYROBP human pred
O00584 O00584 P19397 RNASET2 CD53 human pred
O00584 O00584 Q9GZY6 RNASET2 LAT2 human pred
O00584 O00584 P09917 RNASET2 ALOX5 human pred
O00584 O00584 P52815 RNASET2 MRPL12 human exp
O00584 O00584 O14745 RNASET2 SLC9A3R1 human exp
O00584 O00584 Q9UK22 RNASET2 FBXO2 human exp
O00584 O00584 P14317 RNASET2 HCLS1 human pred
O00584 O00584 P30273 RNASET2 FCER1G human pred
O00584 O00584 P30048 RNASET2 PRDX3 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.