Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 285 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
O00716 O00716 Q75T13 E2F3 PGAP1 human exp
O00716 O00716 P33991 E2F3 MCM4 human exp
O00716 O00716 Q15029 E2F3 EFTUD2 human exp
O00716 O00716 Q9UH99 E2F3 SUN2 human exp
O00716 O00716 P10244 E2F3 MYBL2 human exp,pred
O00716 O00716 Q5XKR4 E2F3 OTP human pred
O00716 O00716 Q8TAT6 E2F3 NPLOC4 human exp
O00716 O00716 Q9H2F5 E2F3 EPC1 human pred
O00716 O00716 Q92793 E2F3 CREBBP human exp,pred
O00716 O00716 P54821 E2F3 PRRX1 human pred
O00716 O00716 P43246 E2F3 MSH2 human exp
O00716 O00716 P29218 E2F3 IMPA1 human exp
O00716 O00716 Q7Z460 E2F3 CLASP1 human exp
O00716 O00716 Q01892 E2F3 SPIB human exp
O00716 O00716 P14635 E2F3 CCNB1 human exp
O00716 O00716 P19532 E2F3 TFE3 human exp
O00716 O00716 P28358 E2F3 HOXD10 human pred
O00716 O00716 Q01851 E2F3 POU4F1 human pred
O00716 O00716 Q9BPX3 E2F3 NCAPG human exp
O00716 O00716 Q9HD15 E2F3 SRA1 human exp
O00716 O00716 Q9HCL2 E2F3 GPAM human exp
O00716 O00716 P35232 E2F3 PHB human pred
O00716 O00716 P31249 E2F3 HOXD3 human pred
O00716 O00716 P11021 E2F3 HSPA5 human exp
O00716 O00716 P38398 E2F3 BRCA1 human pred
O00716 O00716 Q14192 E2F3 FHL2 human exp
O00716 O00716 Q9Y6V0 E2F3 PCLO human exp
O00716 O00716 P23396 E2F3 RPS3 human exp
O00716 O00716 Q9Y3T9 E2F3 NOC2L human exp
O00716 O00716 Q9Y4A5 E2F3 TRRAP human exp
O00716 O00716 Q16667 E2F3 CDKN3 human pred
O00716 O00716 Q9UHJ3 E2F3 SFMBT1 human exp
O00716 O00716 Q9NXE4 E2F3 SMPD4 human exp
O00716 O00716 P31314 E2F3 TLX1 human pred
O00716 O00716 Q15717 E2F3 ELAVL1 human exp
O00716 O00716 Q14527 E2F3 HLTF human exp
O00716 O00716 P20226 E2F3 TBP human pred
O00716 O00716 P50219 E2F3 MNX1 human pred
O00716 O00716 Q56P03 E2F3 EAPP human exp
O00716 O00716 P02533 E2F3 KRT14 human exp
O00716 O00716 P36406 E2F3 TRIM23 human exp
O00716 O00716 Q9NUQ2 E2F3 AGPAT5 human exp
O00716 O00716 P78396 E2F3 CCNA1 human pred
O00716 O00716 O60341 E2F3 KDM1A human exp
O00716 O00716 Q9UM47 E2F3 NOTCH3 human exp
O00716 O00716 P19338 E2F3 NCL human exp
O00716 O00716 Q9NYD6 E2F3 HOXC10 human pred
O00716 O00716 P15172 E2F3 MYOD1 human pred
O00716 O00716 Q9UJW3 E2F3 DNMT3L human exp
O00716 O00716 Q16665 E2F3 HIF1A human pred
O00716 O00716 Q8WYP5 E2F3 AHCTF1 human exp
O00716 O00716 P50613 E2F3 CDK7 human pred
O00716 O00716 Q16891 E2F3 IMMT human exp
O00716 O00716 Q00987 E2F3 MDM2 human pred
O00716 O00716 P50750 E2F3 CDK9 human pred
O00716 O00716 Q9UQ13 E2F3 SHOC2 human exp
O00716 O00716 Q68E01 E2F3 INTS3 human exp
O00716 O00716 P29374 E2F3 ARID4A human pred
O00716 O00716 Q71UM5 E2F3 RPS27L human exp
O00716 O00716 Q08211 E2F3 DHX9 human exp
O00716 O00716 P84022 E2F3 SMAD3 human pred
O00716 O00716 Q9UBX3 E2F3 SLC25A10 human exp
O00716 O00716 Q9H0E9 E2F3 BRD8 human exp
O00716 O00716 P30279 E2F3 CCND2 human pred
O00716 O00716 Q16254 E2F3 E2F4 human exp,pred
O00716 O00716 O75030 E2F3 MITF human pred
O00716 O00716 P51610 E2F3 HCFC1 human exp
O00716 O00716 P12004 E2F3 PCNA human exp
O00716 O00716 P11166 E2F3 SLC2A1 human exp
O00716 O00716 O14776 E2F3 TCERG1 human exp
O00716 O00716 P35527 E2F3 KRT9 human exp
O00716 O00716 P50876 E2F3 RNF144A human exp
O00716 O00716 O15151 E2F3 MDM4 human pred
O00716 O00716 P78367 E2F3 NKX3-2 human pred
O00716 O00716 P29084 E2F3 GTF2E2 human pred
O00716 O00716 Q96FV9 E2F3 THOC1 human pred
O00716 O00716 Q9UL03 E2F3 INTS6 human exp
O00716 O00716 Q96RE9 E2F3 ZNF300 human exp
O00716 O00716 P26358 E2F3 DNMT1 human pred
O00716 O00716 Q9UJV9 E2F3 DDX41 human exp
O00716 O00716 Q14686 E2F3 NCOA6 human pred
O00716 O00716 Q9NR30 E2F3 DDX21 human exp
O00716 O00716 P06400 E2F3 RB1 human exp,ortho,pred
O00716 O00716 P43304 E2F3 GPD2 human exp
O00716 O00716 P43699 E2F3 NKX2-1 human pred
O00716 O00716 A0AVK6 E2F3 E2F8 human pred
O00716 O00716 O15427 E2F3 SLC16A3 human exp
O00716 O00716 Q13309 E2F3 SKP2 human pred
O00716 O00716 P49848 E2F3 TAF6 human pred
O00716 O00716 Q96GD4 E2F3 AURKB human pred
O00716 O00716 Q9BQG0 E2F3 MYBBP1A human exp
O00716 O00716 P78527 E2F3 PRKDC human exp
O00716 O00716 O75832 E2F3 PSMD10 human pred
O00716 O00716 P13378 E2F3 HOXD8 human pred
O00716 O00716 O43823 E2F3 AKAP8 human exp
O00716 O00716 Q99741 E2F3 CDC6 human exp
O00716 O00716 P41182 E2F3 BCL6 human exp
O00716 O00716 Q14978 E2F3 NOLC1 human exp
O00716 O00716 P39880 E2F3 CUX1 human pred
O00716 O00716 Q9NVI7 E2F3 ATAD3A human exp
O00716 O00716 Q9Y4W6 E2F3 AFG3L2 human exp
O00716 O00716 P42704 E2F3 LRPPRC human exp
O00716 O00716 Q16206 E2F3 ENOX2 human exp
O00716 O00716 P00374 E2F3 DHFR human exp
O00716 O00716 Q13263 E2F3 TRIM28 human exp
O00716 O00716 Q00534 E2F3 CDK6 human pred
O00716 O00716 P04264 E2F3 KRT1 human exp
O00716 O00716 Q92922 E2F3 SMARCC1 human pred
O00716 O00716 Q12888 E2F3 TP53BP1 human pred
O00716 O00716 Q9BX10 E2F3 GTPBP2 human exp
O00716 O00716 Q6MZP7 E2F3 LIN54 human pred
O00716 O00716 P35453 E2F3 HOXD13 human pred
O00716 O00716 P24385 E2F3 CCND1 human exp,ortho,pred
O00716 O00716 Q92621 E2F3 NUP205 human exp
O00716 O00716 P02545 E2F3 LMNA human exp
O00716 O00716 Q9NPF5 E2F3 DMAP1 human pred
O00716 O00716 Q92851 E2F3 CASP10 human pred
O00716 O00716 Q99453 E2F3 PHOX2B human pred
O00716 O00716 P17066 E2F3 HSPA6 human exp
O00716 O00716 P04637 E2F3 TP53 human exp,pred
O00716 O00716 Q14980 E2F3 NUMA1 human exp
O00716 O00716 Q9BQC6 E2F3 MRPL57 human exp
O00716 O00716 Q9UQ80 E2F3 PA2G4 human pred
O00716 O00716 Q969R5 E2F3 L3MBTL2 human exp
O00716 O00716 Q5VVJ2 E2F3 MYSM1 human pred
O00716 O00716 Q9C010 E2F3 PKIB human exp
O00716 O00716 P02768 E2F3 ALB human exp
O00716 O00716 P30305 E2F3 CDC25B human exp
O00716 O00716 P43243 E2F3 MATR3 human exp
O00716 O00716 Q9NY61 E2F3 AATF human pred
O00716 O00716 Q09472 E2F3 EP300 human pred
O00716 O00716 O00159 E2F3 MYO1C human exp
O00716 O00716 Q8IWI9 E2F3 MGA human exp
O00716 O00716 Q9UQR1 E2F3 ZNF148 human exp
O00716 O00716 Q9UM54 E2F3 MYO6 human exp
O00716 O00716 Q08050 E2F3 FOXM1 human pred
O00716 O00716 P17676 E2F3 CEBPB human pred
O00716 O00716 Q92769 E2F3 HDAC2 human pred
O00716 O00716 P24941 E2F3 CDK2 human pred
O00716 O00716 O00767 E2F3 SCD human exp
O00716 O00716 P35222 E2F3 CTNNB1 human exp
O00716 O00716 P20248 E2F3 CCNA2 human exp,ortho,pred
O00716 O00716 Q14209 E2F3 E2F2 human pred
O00716 O00716 Q8TDN4 E2F3 CABLES1 human pred
O00716 O00716 P09016 E2F3 HOXD4 human pred
O00716 O00716 Q09028 E2F3 RBBP4 human pred
O00716 O00716 Q13485 E2F3 SMAD4 human pred
O00716 O00716 P28331 E2F3 NDUFS1 human exp
O00716 O00716 Q99594 E2F3 TEAD3 human exp
O00716 O00716 P52701 E2F3 MSH6 human exp
O00716 O00716 O75152 E2F3 ZC3H11A human exp
O00716 O00716 P49715 E2F3 CEBPA human pred
O00716 O00716 P28749 E2F3 RBL1 human exp,pred
O00716 O00716 Q9Y3X0 E2F3 CCDC9 human exp
O00716 O00716 Q01094 E2F3 E2F1 human exp,pred
O00716 O00716 O43365 E2F3 HOXA3 human pred
O00716 O00716 P0C0S8 E2F3 HIST1H2AG human pred
O00716 O00716 P52952 E2F3 NKX2-5 human pred
O00716 O00716 P12956 E2F3 XRCC6 human exp
O00716 O00716 Q99543 E2F3 DNAJC2 human pred
O00716 O00716 Q13029 E2F3 PRDM2 human pred
O00716 O00716 Q8TAU0 E2F3 NKX2-3 human pred
O00716 O00716 O14757 E2F3 CHEK1 human pred
O00716 O00716 Q66K89 E2F3 E4F1 human pred
O00716 O00716 Q9Y5K5 E2F3 UCHL5 human exp
O00716 O00716 Q9BXJ9 E2F3 NAA15 human pred
O00716 O00716 Q16531 E2F3 DDB1 human exp
O00716 O00716 Q03701 E2F3 CEBPZ human exp
O00716 O00716 P51153 E2F3 RAB13 human exp
O00716 O00716 Q8IXI1 E2F3 RHOT2 human exp
O00716 O00716 Q9H6R0 E2F3 DHX33 human exp
O00716 O00716 Q92994 E2F3 BRF1 human pred
O00716 O00716 P12236 E2F3 SLC25A6 human exp
O00716 O00716 P16219 E2F3 ACADS human exp
O00716 O00716 P29083 E2F3 GTF2E1 human pred
O00716 O00716 P40939 E2F3 HADHA human exp
O00716 O00716 Q9NXR8 E2F3 ING3 human pred
O00716 O00716 Q9H0A0 E2F3 NAT10 human exp
O00716 O00716 Q15906 E2F3 VPS72 human exp
O00716 O00716 Q13330 E2F3 MTA1 human pred
O00716 O00716 O15379 E2F3 HDAC3 human pred
O00716 O00716 Q9NQB0 E2F3 TCF7L2 human exp
O00716 O00716 Q9UM11 E2F3 FZR1 human exp
O00716 O00716 Q14739 E2F3 LBR human exp
O00716 O00716 P57088 E2F3 TMEM33 human exp
O00716 O00716 Q96AV8 E2F3 E2F7 human pred
O00716 O00716 O43795 E2F3 MYO1B human exp
O00716 O00716 O75461 E2F3 E2F6 human pred
O00716 O00716 Q9UIW0 E2F3 VAX2 human pred
O00716 O00716 Q15054 E2F3 POLD3 human exp
O00716 O00716 P05556 E2F3 ITGB1 human exp
O00716 O00716 P50416 E2F3 CPT1A human exp
O00716 O00716 Q8N1F7 E2F3 NUP93 human exp
O00716 O00716 Q06587 E2F3 RING1 human pred
O00716 O00716 P11388 E2F3 TOP2A human pred
O00716 O00716 Q16533 E2F3 SNAPC1 human pred
O00716 O00716 O15350 E2F3 TP73 human pred
O00716 O00716 P54098 E2F3 POLG human exp
O00716 O00716 P35221 E2F3 CTNNA1 human exp
O00716 O00716 O60264 E2F3 SMARCA5 human pred
O00716 O00716 Q00325 E2F3 SLC25A3 human exp
O00716 O00716 P02786 E2F3 TFRC human exp
O00716 O00716 P35869 E2F3 AHR human pred
O00716 O00716 Q8IXI2 E2F3 RHOT1 human exp
O00716 O00716 Q9Y468 E2F3 L3MBTL1 human pred
O00716 O00716 P22415 E2F3 USF1 human exp,ortho
O00716 O00716 P35251 E2F3 RFC1 human exp
O00716 O00716 Q13618 E2F3 CUL3 human pred
O00716 O00716 Q99496 E2F3 RNF2 human pred
O00716 O00716 Q13547 E2F3 HDAC1 human exp,pred
O00716 O00716 Q9H4A3 E2F3 WNK1 human exp
O00716 O00716 P31268 E2F3 HOXA7 human pred
O00716 O00716 P29375 E2F3 KDM5A human pred
O00716 O00716 P09874 E2F3 PARP1 human exp
O00716 O00716 O60563 E2F3 CCNT1 human pred
O00716 O00716 Q9NZ01 E2F3 TECR human exp
O00716 O00716 Q6SJ96 E2F3 TBPL2 human pred
O00716 O00716 Q14186 E2F3 TFDP1 human exp,pred
O00716 O00716 Q6P9B9 E2F3 INTS5 human exp
O00716 O00716 Q16576 E2F3 RBBP7 human pred
O00716 O00716 Q96JM7 E2F3 L3MBTL3 human exp
O00716 O00716 Q92966 E2F3 SNAPC3 human pred
O00716 O00716 Q5TKA1 E2F3 LIN9 human pred
O00716 O00716 P68104 E2F3 EEF1A1 human exp
O00716 O00716 P38646 E2F3 HSPA9 human exp
O00716 O00716 P62987 E2F3 UBA52 human exp
O00716 O00716 P42574 E2F3 CASP3 human pred
O00716 O00716 O60583 E2F3 CCNT2 human pred
O00716 O00716 P33993 E2F3 MCM7 human pred
O00716 O00716 Q6PL18 E2F3 ATAD2 human exp
O00716 O00716 P05141 E2F3 SLC25A5 human exp
O00716 O00716 Q14774 E2F3 HLX human pred
O00716 O00716 A2RU54 E2F3 HMX2 human pred
O00716 O00716 P05412 E2F3 JUN human pred
O00716 O00716 Q9UGL1 E2F3 KDM5B human pred
O00716 O00716 Q14191 E2F3 WRN human exp
O00716 O00716 P14921 E2F3 ETS1 human pred
O00716 O00716 P20265 E2F3 POU3F2 human pred
O00716 O00716 Q13573 E2F3 SNW1 human pred
O00716 O00716 P05023 E2F3 ATP1A1 human exp
O00716 O00716 P28370 E2F3 SMARCA1 human exp
O00716 O00716 O14543 E2F3 SOCS3 human pred
O00716 O00716 Q00839 E2F3 HNRNPU human exp
O00716 O00716 P16615 E2F3 ATP2A2 human exp
O00716 O00716 Q92831 E2F3 KAT2B human pred
O00716 O00716 P00519 E2F3 ABL1 human pred
O00716 O00716 P55265 E2F3 ADAR human pred
O00716 O00716 Q92871 E2F3 PMM1 human exp
O00716 O00716 P61619 E2F3 SEC61A1 human exp
O00716 O00716 Q05925 E2F3 EN1 human pred
O00716 O00716 Q9H1K0 E2F3 RBSN human exp
O00716 O00716 Q08999 E2F3 RBL2 human pred
O00716 O00716 Q6P1M0 E2F3 SLC27A4 human exp
O00716 O00716 P31271 E2F3 HOXA13 human pred
O00716 O00716 P49716 E2F3 CEBPD human pred
O00716 O00716 Q8N488 E2F3 RYBP human exp
O00716 O00716 P52945 E2F3 PDX1 human pred
O00716 O00716 O14948 E2F3 TFEC human pred
O00716 O00716 O75132 E2F3 ZBED4 human exp
O00716 O00716 P21675 E2F3 TAF1 human pred
O00716 O00716 P35659 E2F3 DEK human pred
O00716 O00716 Q9NRZ9 E2F3 HELLS human exp
O00716 O00716 Q14188 E2F3 TFDP2 human exp,pred
O00716 O00716 Q9UBM7 E2F3 DHCR7 human exp
O00716 O00716 Q8NEM0 E2F3 MCPH1 human pred
O00716 O00716 P22105 E2F3 TNXB human exp
O00716 O00716 Q5H9I0 E2F3 TFDP3 human exp,pred
O00716 O00716 O14686 E2F3 KMT2D human exp
O00716 O00716 P12235 E2F3 SLC25A4 human exp
O00716 O00716 P46977 E2F3 STT3A human exp
O00716 O00716 P17480 E2F3 UBTF human pred
O00716 O00716 Q92830 E2F3 KAT2A human exp
O00716 O00716 P25490 E2F3 YY1 human exp
O00716 O00716 P13984 E2F3 GTF2F2 human pred
O00716 O00716 P13010 E2F3 XRCC5 human exp
O00716 O00716 Q00577 E2F3 PURA human pred
O00716 O00716 P11802 E2F3 CDK4 human pred
O00716 O00716 Q8NF50 E2F3 DOCK8 human exp
O00716 O00716 P15336 E2F3 ATF2 human pred
O00716 O00716 Q8IZF2 E2F3 ADGRF5 human exp
O00716 O00716 P09923 E2F3 ALPI human exp
O00716 O00716 Q00526 E2F3 CDK3 human exp
O00716 O00716 P52948 E2F3 NUP98 human exp
O00716 O00716 Q15329 E2F3 E2F5 human pred
O00716 O00716 P08047 E2F3 SP1 human exp,pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.