Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 30 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
O15440 O15440 O60706 ABCC5 ABCC9 human pred
O15440 O15440 O95347 ABCC5 SMC2 human exp
O15440 O15440 P21439 ABCC5 ABCB4 human pred
O15440 O15440 Q14508 ABCC5 WFDC2 human pred
O15440 O15440 Q92887 ABCC5 ABCC2 human pred
O15440 O15440 O15439 ABCC5 ABCC4 human pred
O15440 O15440 Q96J65 ABCC5 ABCC12 human pred
O15440 O15440 Q09428 ABCC5 ABCC8 human pred
O15440 O15440 P45844 ABCC5 ABCG1 human pred
O15440 O15440 P03372 ABCC5 ESR1 human exp
O15440 O15440 Q2M3G0 ABCC5 ABCB5 human pred
O15440 O15440 P82980 ABCC5 RBP5 human exp
O15440 O15440 P54819 ABCC5 AK2 human exp
O15440 O15440 Q9HCE1 ABCC5 MOV10 human exp
O15440 O15440 O95342 ABCC5 ABCB11 human pred
O15440 O15440 Q96J66 ABCC5 ABCC11 human pred
O15440 O15440 P28288 ABCC5 ABCD3 human pred
O15440 O15440 P13569 ABCC5 CFTR human pred
O15440 O15440 Q9UNQ0 ABCC5 ABCG2 human pred
O15440 O15440 Q7Z2H8 ABCC5 SLC36A1 human pred
O15440 O15440 P34897 ABCC5 SHMT2 human exp
O15440 O15440 P33527 ABCC5 ABCC1 human pred
O15440 O15440 Q9UBU9 ABCC5 NXF1 human exp
O15440 O15440 P08183 ABCC5 ABCB1 human pred
O15440 O15440 Q9NP58 ABCC5 ABCB6 human pred
O15440 O15440 Q86X19 ABCC5 TMEM17 human exp
O15440 O15440 Q5T3U5 ABCC5 ABCC10 human pred
O15440 O15440 Q9BVL2 ABCC5 NUP58 human exp
O15440 O15440 O15438 ABCC5 ABCC3 human pred
O15440 O15440 P01011 ABCC5 SERPINA3 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.