Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 269 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P05231 P05231 P01375 IL6 TNF human exp
P05231 P05231 Q8IXL6 IL6 FAM20C human exp
P05231 P05231 Q9UHF4 IL6 IL20RA human pred
P05231 P05231 Q15365 IL6 PCBP1 human ortho
P05231 P05231 P02751 IL6 FN1 human exp,pred
P05231 P05231 P19875 IL6 CXCL2 human pred
P05231 P05231 Q8NI17 IL6 IL31RA human pred
P05231 P05231 Q9UHD0 IL6 IL19 human pred
P05231 P05231 Q9UQC2 IL6 GAB2 human pred
P05231 P05231 P37173 IL6 TGFBR2 human pred
P05231 P05231 P21757 IL6 MSR1 human pred
P05231 P05231 Q03135 IL6 CAV1 human pred
P05231 P05231 Q99062 IL6 CSF3R human pred
P05231 P05231 P02649 IL6 APOE human pred
P05231 P05231 O60885 IL6 BRD4 human pred
P05231 P05231 Q96PK2 IL6 - human pred
P05231 P05231 P35367 IL6 HRH1 human exp
P05231 P05231 Q9UBD9 IL6 CLCF1 human pred
P05231 P05231 Q08830 IL6 FGL1 human pred
P05231 P05231 P05362 IL6 ICAM1 human pred
P05231 P05231 Q08334 IL6 IL10RB human pred
P05231 P05231 Q9BWV1 IL6 BOC human pred
P05231 P05231 Q92752 IL6 TNR human pred
P05231 P05231 Q14005 IL6 IL16 human ortho,pred
P05231 P05231 P78552 IL6 IL13RA1 human pred
P05231 P05231 P01034 IL6 CST3 human pred
P05231 P05231 Q8IWV2 IL6 CNTN4 human pred
P05231 P05231 Q8WZ75 IL6 ROBO4 human pred
P05231 P05231 Q86YW5 IL6 TREML1 human pred
P05231 P05231 P01589 IL6 IL2RA human pred
P05231 P05231 Q9Y616 IL6 IRAK3 human pred
P05231 P05231 P41159 IL6 LEP human pred
P05231 P05231 Q99767 IL6 APBA2 human pred
P05231 P05231 P35354 IL6 PTGS2 human pred
P05231 P05231 P10914 IL6 IRF1 human pred
P05231 P05231 P21580 IL6 TNFAIP3 human pred
P05231 P05231 Q9Y2K7 IL6 KDM2A human pred
P05231 P05231 Q16270 IL6 IGFBP7 human pred
P05231 P05231 Q9Y6Q6 IL6 TNFRSF11A human pred
P05231 P05231 P29459 IL6 IL12A human pred
P05231 P05231 Q13651 IL6 IL10RA human pred
P05231 P05231 Q92570 IL6 NR4A3 human pred
P05231 P05231 Q6P9H4 IL6 CNKSR3 human pred
P05231 P05231 P17275 IL6 JUNB human pred
P05231 P05231 P10909 IL6 CLU human pred
P05231 P05231 Q9HCK4 IL6 ROBO2 human pred
P05231 P05231 O15169 IL6 AXIN1 human pred
P05231 P05231 O43365 IL6 HOXA3 human pred
P05231 P05231 P13726 IL6 F3 human pred
P05231 P05231 Q99650 IL6 OSMR human pred
P05231 P05231 P54760 IL6 EPHB4 human pred
P05231 P05231 P05231 IL6 IL6 human exp
P05231 P05231 Q969J5 IL6 IL22RA2 human pred
P05231 P05231 Q8NET5 IL6 NFAM1 human pred
P05231 P05231 Q495A1 IL6 TIGIT human pred
P05231 P05231 O43187 IL6 IRAK2 human pred
P05231 P05231 P15924 IL6 DSP human pred
P05231 P05231 P00738 IL6 HP human pred
P05231 P05231 Q71H61 IL6 ILDR2 human pred
P05231 P05231 P20809 IL6 IL11 human pred
P05231 P05231 P04233 IL6 CD74 human pred
P05231 P05231 P35225 IL6 IL13 human pred
P05231 P05231 P01024 IL6 C3 human pred
P05231 P05231 Q9BWW8 IL6 APOL6 human pred
P05231 P05231 P26447 IL6 S100A4 human pred
P05231 P05231 P07204 IL6 THBD human pred
P05231 P05231 Q96MS0 IL6 ROBO3 human pred
P05231 P05231 O15111 IL6 CHUK human pred
P05231 P05231 Q15761 IL6 NPY5R human pred
P05231 P05231 P26441 IL6 CNTF human pred
P05231 P05231 P13725 IL6 OSM human exp,pred
P05231 P05231 P17948 IL6 FLT1 human pred
P05231 P05231 P10451 IL6 SPP1 human pred
P05231 P05231 P19876 IL6 CXCL3 human pred
P05231 P05231 P41220 IL6 RGS2 human pred
P05231 P05231 P26992 IL6 CNTFR human pred
P05231 P05231 P10145 IL6 CXCL8 human exp,pred
P05231 P05231 Q15654 IL6 TRIP6 human pred
P05231 P05231 Q04864 IL6 REL human ortho,pred
P05231 P05231 P01241 IL6 GH1 human pred
P05231 P05231 O43709 IL6 BUD23 human pred
P05231 P05231 O60603 IL6 TLR2 human pred
P05231 P05231 Q9UQP3 IL6 TNN human pred
P05231 P05231 Q9NQB0 IL6 TCF7L2 human pred
P05231 P05231 Q8WZ42 IL6 TTN human pred
P05231 P05231 Q9NZC2 IL6 TREM2 human pred
P05231 P05231 P60568 IL6 IL2 human pred
P05231 P05231 Q9Y618 IL6 NCOR2 human pred
P05231 P05231 P35968 IL6 KDR human pred
P05231 P05231 P02735 IL6 - human pred
P05231 P05231 P01584 IL6 IL1B human exp,pred
P05231 P05231 Q96FZ5 IL6 CMTM7 human pred
P05231 P05231 Q9UH65 IL6 SWAP70 human pred
P05231 P05231 O14920 IL6 IKBKB human pred
P05231 P05231 Q9BYH8 IL6 NFKBIZ human exp,pred
P05231 P05231 O60500 IL6 NPHS1 human pred
P05231 P05231 P19838 IL6 NFKB1 human pred
P05231 P05231 Q14774 IL6 HLX human pred
P05231 P05231 P19320 IL6 VCAM1 human pred
P05231 P05231 Q9Y279 IL6 VSIG4 human pred
P05231 P05231 Q9NYY1 IL6 IL20 human pred
P05231 P05231 P14784 IL6 IL2RB human pred
P05231 P05231 Q96P20 IL6 NLRP3 human pred
P05231 P05231 P49771 IL6 FLT3LG human pred
P05231 P05231 P19438 IL6 TNFRSF1A human pred
P05231 P05231 Q92985 IL6 IRF7 human pred
P05231 P05231 P01137 IL6 TGFB1 human pred
P05231 P05231 P10586 IL6 PTPRF human pred
P05231 P05231 Q15109 IL6 AGER human pred
P05231 P05231 Q9UDY8 IL6 MALT1 human pred
P05231 P05231 O14791 IL6 APOL1 human pred
P05231 P05231 P31151 IL6 S100A7 human pred
P05231 P05231 P15018 IL6 LIF human exp,pred
P05231 P05231 P42081 IL6 CD86 human pred
P05231 P05231 O60674 IL6 JAK2 human pred
P05231 P05231 Q9HCY8 IL6 S100A14 human pred
P05231 P05231 P78423 IL6 CX3CL1 human pred
P05231 P05231 P55290 IL6 CDH13 human pred
P05231 P05231 Q6UWB1 IL6 IL27RA human pred
P05231 P05231 Q9Y2T1 IL6 AXIN2 human pred
P05231 P05231 P81172 IL6 HAMP human pred
P05231 P05231 P49913 IL6 CAMP human pred
P05231 P05231 Q99962 IL6 SH3GL2 human exp
P05231 P05231 P05113 IL6 IL5 human pred
P05231 P05231 Q96CX2 IL6 KCTD12 human pred
P05231 P05231 P01732 IL6 CD8A human pred
P05231 P05231 P20749 IL6 BCL3 human pred
P05231 P05231 O95727 IL6 CRTAM human pred
P05231 P05231 P16471 IL6 PRLR human pred
P05231 P05231 Q6IA17 IL6 SIGIRR human pred
P05231 P05231 Q5ZPR3 IL6 CD276 human pred
P05231 P05231 Q9UPW6 IL6 SATB2 human pred
P05231 P05231 Q14213 IL6 EBI3 human pred
P05231 P05231 Q9Y2G2 IL6 CARD8 human pred
P05231 P05231 P07766 IL6 CD3E human pred
P05231 P05231 Q4KMG0 IL6 CDON human pred
P05231 P05231 Q9HBE4 IL6 IL21 human pred
P05231 P05231 P21675 IL6 TAF1 human pred
P05231 P05231 P42701 IL6 IL12RB1 human pred
P05231 P05231 Q9Y6N7 IL6 ROBO1 human pred
P05231 P05231 P18428 IL6 LBP human pred
P05231 P05231 P60321 IL6 NANOS2 human pred
P05231 P05231 P06850 IL6 CRH human pred
P05231 P05231 P51617 IL6 IRAK1 human pred
P05231 P05231 P40238 IL6 MPL human pred
P05231 P05231 P49716 IL6 CEBPD human ortho
P05231 P05231 Q9NTI2 IL6 ATP8A2 human exp
P05231 P05231 P31946 IL6 YWHAB human pred
P05231 P05231 P48061 IL6 CXCL12 human pred
P05231 P05231 P47712 IL6 PLA2G4A human pred
P05231 P05231 P61916 IL6 NPC2 human pred
P05231 P05231 P54753 IL6 EPHB3 human pred
P05231 P05231 P01574 IL6 IFNB1 human pred
P05231 P05231 P13501 IL6 CCL5 human pred
P05231 P05231 P01023 IL6 A2M human exp,pred
P05231 P05231 P40933 IL6 IL15 human exp,pred
P05231 P05231 P10747 IL6 CD28 human pred
P05231 P05231 P46695 IL6 IER3 human pred
P05231 P05231 Q53EP0 IL6 FNDC3B human pred
P05231 P05231 P00519 IL6 ABL1 human pred
P05231 P05231 Q14626 IL6 IL11RA human pred
P05231 P05231 O75144 IL6 ICOSLG human pred
P05231 P05231 P52333 IL6 JAK3 human pred
P05231 P05231 P40225 IL6 THPO human pred
P05231 P05231 P08887 IL6 IL6R human exp,pred
P05231 P05231 Q29980 IL6 MICB human pred
P05231 P05231 Q92859 IL6 NEO1 human pred
P05231 P05231 P43146 IL6 DCC human pred
P05231 P05231 P05112 IL6 IL4 human pred
P05231 P05231 P32927 IL6 CSF2RB human pred
P05231 P05231 Q9BZS1 IL6 FOXP3 human ortho
P05231 P05231 P15813 IL6 CD1D human pred
P05231 P05231 P49767 IL6 VEGFC human pred
P05231 P05231 Q12913 IL6 PTPRJ human pred
P05231 P05231 Q9UP38 IL6 FZD1 human pred
P05231 P05231 P16410 IL6 CTLA4 human pred
P05231 P05231 Q9BY67 IL6 CADM1 human pred
P05231 P05231 P09919 IL6 CSF3 human pred
P05231 P05231 Q92729 IL6 PTPRU human pred
P05231 P05231 O14543 IL6 SOCS3 human pred
P05231 P05231 P13500 IL6 CCL2 human pred
P05231 P05231 P16144 IL6 ITGB4 human pred
P05231 P05231 Q01151 IL6 CD83 human pred
P05231 P05231 P12272 IL6 PTHLH human exp,pred
P05231 P05231 P13232 IL6 IL7 human pred
P05231 P05231 P21333 IL6 FLNA human pred
P05231 P05231 P21730 IL6 C5AR1 human pred
P05231 P05231 P01588 IL6 EPO human pred
P05231 P05231 P61981 IL6 YWHAG human pred
P05231 P05231 P17181 IL6 IFNAR1 human pred
P05231 P05231 Q9NX02 IL6 NLRP2 human pred
P05231 P05231 P02652 IL6 APOA2 human pred
P05231 P05231 P07948 IL6 LYN human pred
P05231 P05231 P29460 IL6 IL12B human pred
P05231 P05231 Q9BQ51 IL6 PDCD1LG2 human pred
P05231 P05231 P02671 IL6 FGA human pred
P05231 P05231 P11169 IL6 SLC2A3 human pred
P05231 P05231 Q9NP99 IL6 TREM1 human pred
P05231 P05231 Q9HC29 IL6 NOD2 human pred
P05231 P05231 P24394 IL6 IL4R human pred
P05231 P05231 P30411 IL6 BDKRB2 human pred
P05231 P05231 Q9UHR4 IL6 BAIAP2L1 human pred
P05231 P05231 P01236 IL6 PRL human pred
P05231 P05231 P04141 IL6 CSF2 human pred
P05231 P05231 P29275 IL6 ADORA2B human pred
P05231 P05231 Q05516 IL6 ZBTB16 human exp
P05231 P05231 Q15717 IL6 ELAVL1 human pred
P05231 P05231 Q9UQ49 IL6 NEU3 human pred
P05231 P05231 Q9H257 IL6 CARD9 human pred
P05231 P05231 P07996 IL6 THBS1 human pred
P05231 P05231 Q8TDS4 IL6 HCAR2 human pred
P05231 P05231 P09341 IL6 CXCL1 human pred
P05231 P05231 P22105 IL6 TNXB human pred
P05231 P05231 P17676 IL6 CEBPB human exp,pred
P05231 P05231 O94856 IL6 NFASC human pred
P05231 P05231 Q14896 IL6 MYBPC3 human pred
P05231 P05231 Q14289 IL6 PTK2B human pred
P05231 P05231 P42229 IL6 STAT5A human pred
P05231 P05231 P04626 IL6 ERBB2 human pred
P05231 P05231 P23469 IL6 PTPRE human pred
P05231 P05231 Q99665 IL6 IL12RB2 human pred
P05231 P05231 P40763 IL6 STAT3 human exp,ortho
P05231 P05231 Q09472 IL6 EP300 human pred
P05231 P05231 P08700 IL6 IL3 human exp,pred
P05231 P05231 P29320 IL6 EPHA3 human pred
P05231 P05231 O14756 IL6 HSD17B6 human pred
P05231 P05231 Q4ZHG4 IL6 FNDC1 human pred
P05231 P05231 Q92750 IL6 TAF4B human pred
P05231 P05231 Q9Y239 IL6 NOD1 human pred
P05231 P05231 P11684 IL6 SCGB1A1 human pred
P05231 P05231 P10966 IL6 CD8B human pred
P05231 P05231 P01100 IL6 FOS human pred
P05231 P05231 Q99715 IL6 COL12A1 human pred
P05231 P05231 P22614 IL6 - human pred
P05231 P05231 P18847 IL6 ATF3 human ortho,pred
P05231 P05231 Q86WN2 IL6 IFNE human pred
P05231 P05231 Q7Z6A9 IL6 BTLA human pred
P05231 P05231 Q04206 IL6 RELA human pred
P05231 P05231 P05015 IL6 IFNA16 human pred
P05231 P05231 P25963 IL6 NFKBIA human pred
P05231 P05231 Q9NPF7 IL6 IL23A human pred
P05231 P05231 P15692 IL6 VEGFA human exp
P05231 P05231 O95999 IL6 BCL10 human pred
P05231 P05231 P42702 IL6 LIFR human pred
P05231 P05231 P10912 IL6 GHR human pred
P05231 P05231 P61769 IL6 B2M human pred
P05231 P05231 P40189 IL6 IL6ST human exp,ortho,pred
P05231 P05231 P16871 IL6 IL7R human pred
P05231 P05231 Q9GZX6 IL6 IL22 human pred
P05231 P05231 O14931 IL6 NCR3 human pred
P05231 P05231 P82914 IL6 MRPS15 human pred
P05231 P05231 P27540 IL6 ARNT human pred
P05231 P05231 O15554 IL6 KCNN4 human pred
P05231 P05231 Q9NQ38 IL6 SPINK5 human pred
P05231 P05231 Q9BQE5 IL6 APOL2 human pred
P05231 P05231 Q14767 IL6 LTBP2 human pred
P05231 P05231 O15197 IL6 EPHB6 human pred
P05231 P05231 Q15375 IL6 EPHA7 human pred
P05231 P05231 P48551 IL6 IFNAR2 human pred
P05231 P05231 Q9HBE5 IL6 IL21R human pred
P05231 P05231 P02741 IL6 CRP human exp
P05231 P05231 P98161 IL6 PKD1 human pred
P05231 P05231 P21583 IL6 KITLG human pred
P05231 P05231 Q9Y6A5 IL6 TACC3 human pred
P05231 P05231 P08571 IL6 CD14 human exp
P05231 P05231 Q03169 IL6 TNFAIP2 human pred
P05231 P05231 P22301 IL6 IL10 human pred
P05231 P05231 P17861 IL6 XBP1 human ortho,pred
P05231 P05231 Q9NPH9 IL6 IL26 human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.