Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 28 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P06727 P06727 P02652 APOA4 APOA2 human pred
P06727 P06727 P11597 APOA4 CETP human pred
P06727 P06727 P06727 APOA4 APOA4 human exp
P06727 P06727 P02765 APOA4 AHSG human pred
P06727 P06727 P35527 APOA4 KRT9 human pred
P06727 P06727 P01614 APOA4 IGKV2D-40 human pred
P06727 P06727 P35575 APOA4 G6PC human exp
P06727 P06727 Q9GZM6 APOA4 OR8D2 human pred
P06727 P06727 P20393 APOA4 NR1D1 human exp
P06727 P06727 P02768 APOA4 ALB human exp,pred
P06727 P06727 P04264 APOA4 KRT1 human pred
P06727 P06727 P62258 APOA4 YWHAE human ortho
P06727 P06727 P02538 APOA4 KRT6A human pred
P06727 P06727 P62136 APOA4 PPP1CA human ortho
P06727 P06727 P02649 APOA4 APOE human pred
P06727 P06727 P13645 APOA4 KRT10 human pred
P06727 P06727 P55899 APOA4 FCGRT human pred
P06727 P06727 P02654 APOA4 APOC1 human pred
P06727 P06727 Q7Z333 APOA4 SETX human pred
P06727 P06727 Q6Q788 APOA4 APOA5 human pred
P06727 P06727 P00734 APOA4 F2 human pred
P06727 P06727 Q9H974 APOA4 QTRT2 human pred
P06727 P06727 P02671 APOA4 FGA human pred
P06727 P06727 P02766 APOA4 TTR human pred
P06727 P06727 Q9Y4G6 APOA4 TLN2 human pred
P06727 P06727 P02533 APOA4 KRT14 human pred
P06727 P06727 P02647 APOA4 APOA1 human pred
P06727 P06727 P02656 APOA4 APOC3 human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.