Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 33 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P10109 P10109 O43766 FDX1 LIAS human pred
P10109 P10109 Q96G61 FDX1 NUDT11 human pred
P10109 P10109 P99999 FDX1 CYCS human exp,pred
P10109 P10109 O95479 FDX1 H6PD human pred
P10109 P10109 P52895 FDX1 AKR1C2 human pred
P10109 P10109 P10109 FDX1 FDX1 human exp,pred
P10109 P10109 P40926 FDX1 MDH2 human pred
P10109 P10109 Q16134 FDX1 ETFDH human pred
P10109 P10109 P19099 FDX1 CYP11B2 human exp
P10109 P10109 Q16698 FDX1 DECR1 human pred
P10109 P10109 Q03393 FDX1 PTS human pred
P10109 P10109 Q8IWL3 FDX1 HSCB human exp
P10109 P10109 P06576 FDX1 ATP5B human exp
P10109 P10109 Q16665 FDX1 HIF1A human exp
P10109 P10109 Q9UKJ3 FDX1 GPATCH8 human exp
P10109 P10109 Q13515 FDX1 BFSP2 human pred
P10109 P10109 O43741 FDX1 PRKAB2 human exp
P10109 P10109 Q16740 FDX1 CLPP human exp,pred
P10109 P10109 P05108 FDX1 CYP11A1 human exp
P10109 P10109 O15235 FDX1 MRPS12 human pred
P10109 P10109 P43354 FDX1 NR4A2 human exp
P10109 P10109 Q9NWU1 FDX1 OXSM human pred
P10109 P10109 Q8IVT5 FDX1 KSR1 human exp
P10109 P10109 P25705 FDX1 ATP5A1 human exp
P10109 P10109 P50914 FDX1 RPL14 human pred
P10109 P10109 Q04760 FDX1 GLO1 human pred
P10109 P10109 P22570 FDX1 FDXR human pred
P10109 P10109 Q9NR80 FDX1 ARHGEF4 human pred
P10109 P10109 Q6P4F2 FDX1 FDX2 human exp,pred
P10109 P10109 P09467 FDX1 FBP1 human pred
P10109 P10109 O43681 FDX1 ASNA1 human pred
P10109 P10109 P47755 FDX1 CAPZA2 human exp
P10109 P10109 P31040 FDX1 SDHA human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.