Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 19 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P11597 P11597 P07996 CETP THBS1 human pred
P11597 P11597 P06727 CETP APOA4 human pred
P11597 P11597 P41159 CETP LEP human pred
P11597 P11597 P11597 CETP CETP human exp
P11597 P11597 O15145 CETP ARPC3 human exp
P11597 P11597 Q9H0A0 CETP NAT10 human pred
P11597 P11597 P21757 CETP MSR1 human pred
P11597 P11597 P11150 CETP LIPC human pred
P11597 P11597 P02649 CETP APOE human exp,pred
P11597 P11597 P07307 CETP ASGR2 human pred
P11597 P11597 Q13133 CETP NR1H3 human pred
P11597 P11597 Q01844 CETP EWSR1 human exp
P11597 P11597 P06858 CETP LPL human exp,pred
P11597 P11597 O14746 CETP TERT human pred
P11597 P11597 P22612 CETP PRKACG human exp
P11597 P11597 P02647 CETP APOA1 human exp,pred
P11597 P11597 P28845 CETP HSD11B1 human exp
P11597 P11597 P04637 CETP TP53 human exp
P11597 P11597 P55058 CETP PLTP human exp,pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.