Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 31 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P16050 P16050 P09960 ALOX15 LTA4H human pred
P16050 P16050 P35354 ALOX15 PTGS2 human pred
P16050 P16050 P04054 ALOX15 PLA2G1B human pred
P16050 P16050 P30086 ALOX15 PEBP1 human exp
P16050 P16050 Q9NZK7 ALOX15 PLA2G2E human pred
P16050 P16050 P37231 ALOX15 PPARG human pred
P16050 P16050 P78527 ALOX15 PRKDC human exp
P16050 P16050 O15296 ALOX15 ALOX15B human pred
P16050 P16050 O75342 ALOX15 ALOX12B human pred
P16050 P16050 P39877 ALOX15 PLA2G5 human pred
P16050 P16050 Q9UNK4 ALOX15 PLA2G2D human pred
P16050 P16050 P78329 ALOX15 CYP4F2 human pred
P16050 P16050 O43149 ALOX15 ZZEF1 human pred
P16050 P16050 P24462 ALOX15 CYP3A7 human pred
P16050 P16050 Q15365 ALOX15 PCBP1 human pred
P16050 P16050 Q9UMR2 ALOX15 DDX19B human exp
P16050 P16050 Q9BZM2 ALOX15 PLA2G2F human pred
P16050 P16050 Q08477 ALOX15 CYP4F3 human pred
P16050 P16050 Q02928 ALOX15 CYP4A11 human pred
P16050 P16050 Q9BYJ1 ALOX15 ALOXE3 human pred
P16050 P16050 Q99735 ALOX15 MGST2 human pred
P16050 P16050 Q9NZ20 ALOX15 PLA2G3 human pred
P16050 P16050 P23219 ALOX15 PTGS1 human pred
P16050 P16050 P09917 ALOX15 ALOX5 human pred
P16050 P16050 O15496 ALOX15 PLA2G10 human pred
P16050 P16050 P05112 ALOX15 IL4 human pred
P16050 P16050 Q16873 ALOX15 LTC4S human pred
P16050 P16050 P20292 ALOX15 ALOX5AP human pred
P16050 P16050 P10632 ALOX15 CYP2C8 human pred
P16050 P16050 Q5VV67 ALOX15 PPRC1 human pred
P16050 P16050 P18054 ALOX15 ALOX12 human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.