Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 69 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P16435 P16435 O75844 POR ZMPSTE24 human ortho
P16435 P16435 P05181 POR CYP2E1 human exp
P16435 P16435 Q02809 POR PLOD1 human exp
P16435 P16435 Q9BUN8 POR DERL1 human exp
P16435 P16435 P11509 POR CYP2A6 human exp
P16435 P16435 P09601 POR HMOX1 human exp
P16435 P16435 P55209 POR NAP1L1 human ortho
P16435 P16435 O43174 POR CYP26A1 human pred
P16435 P16435 P16435 POR POR human exp,pred
P16435 P16435 Q9P0L0 POR VAPA human exp
P16435 P16435 Q00597 POR FANCC human exp,ortho
P16435 P16435 P33261 POR CYP2C19 human exp
P16435 P16435 P18074 POR ERCC2 human ortho
P16435 P16435 Q01844 POR EWSR1 human exp
P16435 P16435 Q6PI48 POR DARS2 human exp
P16435 P16435 P99999 POR CYCS human exp
P16435 P16435 O14735 POR CDIPT human ortho
P16435 P16435 P22570 POR FDXR human pred
P16435 P16435 P14618 POR PKM human ortho
P16435 P16435 Q8IWU2 POR LMTK2 human pred
P16435 P16435 P08238 POR HSP90AB1 human pred
P16435 P16435 P49768 POR PSEN1 human pred
P16435 P16435 Q9Y6M9 POR NDUFB9 human exp
P16435 P16435 P63104 POR YWHAZ human ortho
P16435 P16435 Q92813 POR DIO2 human pred
P16435 P16435 P35228 POR NOS2 human pred
P16435 P16435 P11712 POR CYP2C9 human exp
P16435 P16435 Q9NQY0 POR BIN3 human ortho
P16435 P16435 P49821 POR NDUFV1 human exp
P16435 P16435 Q9BZV1 POR UBXN6 human exp
P16435 P16435 Q9H7B2 POR RPF2 human ortho
P16435 P16435 P10635 POR CYP2D6 human exp
P16435 P16435 P62191 POR PSMC1 human ortho
P16435 P16435 Q6NUS6 POR TCTN3 human exp
P16435 P16435 P00167 POR CYB5A human exp
P16435 P16435 P0CG48 POR UBC human ortho
P16435 P16435 P25685 POR DNAJB1 human ortho
P16435 P16435 Q86UK5 POR EVC2 human exp
P16435 P16435 Q9GZP9 POR DERL2 human exp
P16435 P16435 P47712 POR PLA2G4A human ortho,pred
P16435 P16435 Q9Y5M8 POR SRPRB human exp
P16435 P16435 O15503 POR INSIG1 human exp
P16435 P16435 Q13153 POR PAK1 human ortho
P16435 P16435 Q96GX1 POR TCTN2 human exp
P16435 P16435 Q04656 POR ATP7A human pred
P16435 P16435 Q7KYR7 POR BTN2A1 human exp
P16435 P16435 Q9P0N5 POR TMEM216 human exp
P16435 P16435 P04629 POR NTRK1 human exp
P16435 P16435 O43242 POR PSMD3 human pred
P16435 P16435 P29536 POR LMOD1 human pred
P16435 P16435 P12956 POR XRCC6 human exp
P16435 P16435 Q8NFF5 POR FLAD1 human ortho
P16435 P16435 Q16850 POR CYP51A1 human ortho
P16435 P16435 P08684 POR CYP3A4 human exp
P16435 P16435 Q7Z6M1 POR RABEPK human exp
P16435 P16435 P05093 POR CYP17A1 human exp,pred
P16435 P16435 P05177 POR CYP1A2 human exp
P16435 P16435 O00264 POR PGRMC1 human exp
P16435 P16435 Q9H2F3 POR HSD3B7 human ortho
P16435 P16435 O00487 POR PSMD14 human ortho
P16435 P16435 P60604 POR UBE2G2 human ortho
P16435 P16435 P62258 POR YWHAE human ortho
P16435 P16435 O00471 POR EXOC5 human ortho
P16435 P16435 O14980 POR XPO1 human exp
P16435 P16435 Q6DD88 POR ATL3 human exp
P16435 P16435 O60568 POR PLOD3 human exp
P16435 P16435 Q86TM6 POR SYVN1 human exp
P16435 P16435 P34932 POR HSPA4 human ortho
P16435 P16435 P42224 POR STAT1 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.