Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 63 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P16519 P16519 P00751 PCSK2 CFB human pred
P16519 P16519 Q8NBP7 PCSK2 PCSK9 human pred
P16519 P16519 Q16549 PCSK2 PCSK7 human pred
P16519 P16519 Q9BR01 PCSK2 SULT4A1 human pred
P16519 P16519 Q9NWB1 PCSK2 RBFOX1 human pred
P16519 P16519 O95670 PCSK2 ATP6V1G2 human pred
P16519 P16519 Q99867 PCSK2 - human pred
P16519 P16519 Q9P2U7 PCSK2 SLC17A7 human pred
P16519 P16519 Q14576 PCSK2 ELAVL3 human pred
P16519 P16519 Q9UI15 PCSK2 TAGLN3 human pred
P16519 P16519 O94805 PCSK2 ACTL6B human pred
P16519 P16519 Q9UPV7 PCSK2 PHF24 human pred
P16519 P16519 P21579 PCSK2 SYT1 human pred
P16519 P16519 Q9UNE7 PCSK2 STUB1 human pred
P16519 P16519 P62258 PCSK2 YWHAE human ortho
P16519 P16519 Q93045 PCSK2 STMN2 human pred
P16519 P16519 Q16352 PCSK2 INA human pred
P16519 P16519 O60641 PCSK2 SNAP91 human pred
P16519 P16519 O60282 PCSK2 KIF5C human pred
P16519 P16519 Q12933 PCSK2 TRAF2 human pred
P16519 P16519 P29122 PCSK2 PCSK6 human pred
P16519 P16519 Q9Y328 PCSK2 NSG2 human pred
P16519 P16519 Q9NY72 PCSK2 SCN3B human pred
P16519 P16519 Q2M2I8 PCSK2 AAK1 human pred
P16519 P16519 P16870 PCSK2 CPE human pred
P16519 P16519 P10645 PCSK2 CHGA human pred
P16519 P16519 P10997 PCSK2 IAPP human exp,pred
P16519 P16519 Q92824 PCSK2 PCSK5 human pred
P16519 P16519 Q13131 PCSK2 PRKAA1 human ortho
P16519 P16519 Q8NER5 PCSK2 ACVR1C human pred
P16519 P16519 P60880 PCSK2 SNAP25 human pred
P16519 P16519 P11216 PCSK2 PYGB human pred
P16519 P16519 Q9UL68 PCSK2 MYT1L human pred
P16519 P16519 Q7L0J3 PCSK2 SV2A human pred
P16519 P16519 Q9BRR3 PCSK2 TMEM246 human pred
P16519 P16519 Q12840 PCSK2 KIF5A human pred
P16519 P16519 Q9UIV8 PCSK2 SERPINB13 human pred
P16519 P16519 P08247 PCSK2 SYP human pred
P16519 P16519 Q13387 PCSK2 MAPK8IP2 human pred
P16519 P16519 Q59EK9 PCSK2 RUNDC3A human pred
P16519 P16519 Q7Z2D5 PCSK2 PLPPR4 human pred
P16519 P16519 Q8NCB2 PCSK2 CAMKV human pred
P16519 P16519 O75914 PCSK2 PAK3 human pred
P16519 P16519 Q8TDI0 PCSK2 CHD5 human pred
P16519 P16519 P07196 PCSK2 NEFL human pred
P16519 P16519 Q92561 PCSK2 PHYHIP human pred
P16519 P16519 P20382 PCSK2 PMCH human exp,pred
P16519 P16519 P61764 PCSK2 STXBP1 human pred
P16519 P16519 P17600 PCSK2 SYN1 human pred
P16519 P16519 P07204 PCSK2 THBD human pred
P16519 P16519 Q9Y478 PCSK2 PRKAB1 human ortho
P16519 P16519 Q9UPP5 PCSK2 KIAA1107 human pred
P16519 P16519 Q9UPA5 PCSK2 BSN human pred
P16519 P16519 P29120 PCSK2 PCSK1 human pred
P16519 P16519 P09958 PCSK2 FURIN human pred
P16519 P16519 P09471 PCSK2 GNAO1 human pred
P16519 P16519 Q8IW70 PCSK2 TMEM151B human pred
P16519 P16519 P05408 PCSK2 SCG5 human exp,pred
P16519 P16519 P16519 PCSK2 PCSK2 human exp
P16519 P16519 Q99784 PCSK2 OLFM1 human pred
P16519 P16519 Q9H2X9 PCSK2 SLC12A5 human pred
P16519 P16519 P00797 PCSK2 REN human pred
P16519 P16519 P35346 PCSK2 SSTR5 human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.