Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 75 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P16520 P16520 P63027 GNB3 VAMP2 human ortho,pred
P16520 P16520 P62879 GNB3 GNB2 human pred
P16520 P16520 O60262 GNB3 GNG7 human exp,pred
P16520 P16520 P19087 GNB3 GNAT2 human pred
P16520 P16520 P49758 GNB3 RGS6 human exp
P16520 P16520 O94810 GNB3 RGS11 human pred
P16520 P16520 Q96J92 GNB3 WNK4 human pred
P16520 P16520 Q9HAV0 GNB3 GNB4 human pred
P16520 P16520 P50151 GNB3 GNG10 human exp
P16520 P16520 O43307 GNB3 ARHGEF9 human pred
P16520 P16520 P40145 GNB3 ADCY8 human pred
P16520 P16520 Q9NR80 GNB3 ARHGEF4 human pred
P16520 P16520 P49841 GNB3 GSK3B human exp
P16520 P16520 P32302 GNB3 CXCR5 human exp
P16520 P16520 P63211 GNB3 GNGT1 human exp,pred
P16520 P16520 Q9UK08 GNB3 GNG8 human exp
P16520 P16520 P01116 GNB3 KRAS human pred
P16520 P16520 Q03113 GNB3 GNA12 human exp,pred
P16520 P16520 Q9NRM7 GNB3 LATS2 human pred
P16520 P16520 O75916 GNB3 RGS9 human pred
P16520 P16520 P19086 GNB3 GNAZ human pred
P16520 P16520 Q96D21 GNB3 RASD2 human exp
P16520 P16520 P48729 GNB3 CSNK1A1 human exp
P16520 P16520 Q9P2W3 GNB3 GNG13 human exp,pred
P16520 P16520 P08754 GNB3 GNAI3 human exp,pred
P16520 P16520 P25098 GNB3 GRK2 human pred
P16520 P16520 P52739 GNB3 ZNF131 human exp
P16520 P16520 P29992 GNB3 GNA11 human pred
P16520 P16520 P63218 GNB3 GNG5 human exp,pred
P16520 P16520 P09471 GNB3 GNAO1 human pred
P16520 P16520 Q99759 GNB3 MAP3K3 human pred
P16520 P16520 P36897 GNB3 TGFBR1 human exp,pred
P16520 P16520 Q08722 GNB3 CD47 human exp
P16520 P16520 O95718 GNB3 ESRRB human exp
P16520 P16520 Q13480 GNB3 GAB1 human pred
P16520 P16520 P63215 GNB3 GNG3 human exp,pred
P16520 P16520 Q92731 GNB3 ESR2 human exp
P16520 P16520 P11488 GNB3 GNAT1 human pred
P16520 P16520 Q8TCU6 GNB3 PREX1 human pred
P16520 P16520 Q8NFM4 GNB3 ADCY4 human pred
P16520 P16520 Q00722 GNB3 PLCB2 human pred
P16520 P16520 O14775 GNB3 GNB5 human pred
P16520 P16520 P04626 GNB3 ERBB2 human exp
P16520 P16520 P50148 GNB3 GNAQ human exp,pred
P16520 P16520 A8MTJ3 GNB3 GNAT3 human pred
P16520 P16520 P42345 GNB3 MTOR human exp
P16520 P16520 Q9H2Y7 GNB3 ZNF106 human pred
P16520 P16520 P50150 GNB3 GNG4 human exp,pred
P16520 P16520 Q9HB21 GNB3 PLEKHA1 human pred
P16520 P16520 Q14206 GNB3 RCAN2 human exp
P16520 P16520 P49674 GNB3 CSNK1E human exp
P16520 P16520 P25116 GNB3 F2R human pred
P16520 P16520 P38405 GNB3 GNAL human pred
P16520 P16520 P04899 GNB3 GNAI2 human exp,pred
P16520 P16520 O43306 GNB3 ADCY6 human pred
P16520 P16520 Q96N96 GNB3 SPATA13 human pred
P16520 P16520 Q14344 GNB3 GNA13 human pred
P16520 P16520 P63096 GNB3 GNAI1 human pred
P16520 P16520 O95837 GNB3 GNA14 human pred
P16520 P16520 Q495N2 GNB3 SLC36A3 human exp
P16520 P16520 Q99459 GNB3 CDC5L human exp
P16520 P16520 Q9UBI6 GNB3 GNG12 human exp,pred
P16520 P16520 P30679 GNB3 GNA15 human pred
P16520 P16520 P62873 GNB3 GNB1 human pred
P16520 P16520 Q9Y2T1 GNB3 AXIN2 human exp
P16520 P16520 P59768 GNB3 GNG2 human exp,pred
P16520 P16520 O15539 GNB3 RGS5 human pred
P16520 P16520 Q13371 GNB3 PDCL human exp
P16520 P16520 P61952 GNB3 GNG11 human exp,pred
P16520 P16520 O60266 GNB3 ADCY3 human pred
P16520 P16520 O14610 GNB3 GNGT2 human exp,pred
P16520 P16520 O15492 GNB3 RGS16 human pred
P16520 P16520 Q13619 GNB3 CUL4A human exp
P16520 P16520 P63092 GNB3 GNAS human pred
P16520 P16520 P16520 GNB3 GNB3 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.