Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 12 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P21217 P21217 P22083 FUT3 FUT4 human pred
P21217 P21217 P37198 FUT3 NUP62 human pred
P21217 P21217 Q6P4F1 FUT3 FUT10 human pred
P21217 P21217 Q9H3Q3 FUT3 GAL3ST2 human pred
P21217 P21217 Q14203 FUT3 DCTN1 human pred
P21217 P21217 Q9Y231 FUT3 FUT9 human pred
P21217 P21217 Q92185 FUT3 ST8SIA1 human pred
P21217 P21217 P24462 FUT3 CYP3A7 human pred
P21217 P21217 P35558 FUT3 PCK1 human pred
P21217 P21217 P04554 FUT3 PRM2 human pred
P21217 P21217 P51993 FUT3 FUT6 human pred
P21217 P21217 O75431 FUT3 MTX2 human ortho

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.