Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 34 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P25106 P25106 Q04900 ACKR3 CD164 human exp
P25106 P25106 P47900 ACKR3 P2RY1 human pred
P25106 P25106 P51685 ACKR3 CCR8 human pred
P25106 P25106 P32239 ACKR3 CCKBR human pred
P25106 P25106 P51681 ACKR3 CCR5 human pred
P25106 P25106 Q14674 ACKR3 ESPL1 human exp
P25106 P25106 Q86VZ1 ACKR3 P2RY8 human pred
P25106 P25106 P30411 ACKR3 BDKRB2 human pred
P25106 P25106 P61073 ACKR3 CXCR4 human pred
P25106 P25106 Q5U5R9 ACKR3 HECTD2 human exp
P25106 P25106 Q9H255 ACKR3 OR51E2 human pred
P25106 P25106 P25705 ACKR3 ATP5A1 human exp
P25106 P25106 Q9BYD3 ACKR3 MRPL4 human exp
P25106 P25106 P16284 ACKR3 PECAM1 human exp
P25106 P25106 P04201 ACKR3 MAS1 human pred
P25106 P25106 O75947 ACKR3 ATP5H human exp
P25106 P25106 O00398 ACKR3 P2RY10 human pred
P25106 P25106 P21730 ACKR3 C5AR1 human pred
P25106 P25106 P06576 ACKR3 ATP5B human exp
P25106 P25106 P25105 ACKR3 PTAFR human pred
P25106 P25106 P62993 ACKR3 GRB2 human exp
P25106 P25106 P25089 ACKR3 FPR3 human pred
P25106 P25106 P30049 ACKR3 ATP5D human exp
P25106 P25106 Q8N806 ACKR3 UBR7 human exp
P25106 P25106 Q9HC97 ACKR3 GPR35 human pred
P25106 P25106 P46093 ACKR3 GPR4 human pred
P25106 P25106 P21731 ACKR3 TBXA2R human pred
P25106 P25106 O95136 ACKR3 S1PR2 human pred
P25106 P25106 P29033 ACKR3 GJB2 human exp
P25106 P25106 P48061 ACKR3 CXCL12 human pred
P25106 P25106 Q9Y271 ACKR3 CYSLTR1 human pred
P25106 P25106 P51677 ACKR3 CCR3 human pred
P25106 P25106 P48047 ACKR3 ATP5O human exp
P25106 P25106 Q9NQ11 ACKR3 ATP13A2 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.