Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 347 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P27448 P27448 P49137 MARK3 MAPKAPK2 human pred
P27448 P27448 Q05655 MARK3 PRKCD human pred
P27448 P27448 Q9Y2J2 MARK3 EPB41L3 human pred
P27448 P27448 P17948 MARK3 FLT1 human pred
P27448 P27448 P20794 MARK3 MAK human pred
P27448 P27448 Q01973 MARK3 ROR1 human pred
P27448 P27448 Q15208 MARK3 STK38 human pred
P27448 P27448 Q6SA08 MARK3 TSSK4 human pred
P27448 P27448 O14920 MARK3 IKBKB human exp,pred
P27448 P27448 Q9UJ41 MARK3 RABGEF1 human pred
P27448 P27448 O14958 MARK3 CASQ2 human exp
P27448 P27448 Q6P597 MARK3 KLC3 human pred
P27448 P27448 P49759 MARK3 CLK1 human pred
P27448 P27448 O95819 MARK3 MAP4K4 human pred
P27448 P27448 Q9H4A3 MARK3 WNK1 human pred
P27448 P27448 Q9H0H5 MARK3 RACGAP1 human pred
P27448 P27448 Q09013 MARK3 DMPK human pred
P27448 P27448 Q9H8J5 MARK3 MANSC1 human exp
P27448 P27448 Q16513 MARK3 PKN2 human pred
P27448 P27448 Q99459 MARK3 CDC5L human pred
P27448 P27448 P05060 MARK3 CHGB human exp
P27448 P27448 Q9BWU1 MARK3 CDK19 human pred
P27448 P27448 P10398 MARK3 ARAF human pred
P27448 P27448 Q96AD5 MARK3 PNPLA2 human exp
P27448 P27448 Q08345 MARK3 DDR1 human pred
P27448 P27448 Q9Y5P4 MARK3 COL4A3BP human exp
P27448 P27448 P01100 MARK3 FOS human exp
P27448 P27448 P04629 MARK3 NTRK1 human exp
P27448 P27448 Q9Y250 MARK3 LZTS1 human pred
P27448 P27448 Q9UBS0 MARK3 RPS6KB2 human pred
P27448 P27448 O76003 MARK3 GLRX3 human pred
P27448 P27448 O95835 MARK3 LATS1 human pred
P27448 P27448 Q13283 MARK3 G3BP1 human pred
P27448 P27448 Q13177 MARK3 PAK2 human pred
P27448 P27448 Q16816 MARK3 PHKG1 human pred
P27448 P27448 P30291 MARK3 WEE1 human pred
P27448 P27448 Q13671 MARK3 RIN1 human pred
P27448 P27448 P22612 MARK3 PRKACG human pred
P27448 P27448 Q15772 MARK3 SPEG human pred
P27448 P27448 P57059 MARK3 SIK1 human pred
P27448 P27448 Q5SW79 MARK3 CEP170 human pred
P27448 P27448 O75069 MARK3 TMCC2 human exp
P27448 P27448 Q7KZI7 MARK3 MARK2 human exp,pred
P27448 P27448 P41279 MARK3 MAP3K8 human pred
P27448 P27448 Q13972 MARK3 RASGRF1 human exp
P27448 P27448 O94804 MARK3 STK10 human pred
P27448 P27448 Q9BYG5 MARK3 PARD6B human pred
P27448 P27448 Q9P0K1 MARK3 ADAM22 human pred
P27448 P27448 P62987 MARK3 UBA52 human exp
P27448 P27448 P56545 MARK3 CTBP2 human exp
P27448 P27448 P22607 MARK3 FGFR3 human pred
P27448 P27448 P07948 MARK3 LYN human pred
P27448 P27448 Q7Z460 MARK3 CLASP1 human pred
P27448 P27448 Q9UHP3 MARK3 USP25 human pred
P27448 P27448 P19784 MARK3 CSNK2A2 human pred
P27448 P27448 Q9Y243 MARK3 AKT3 human pred
P27448 P27448 Q9H307 MARK3 PNN human pred
P27448 P27448 O14641 MARK3 DVL2 human exp
P27448 P27448 Q99683 MARK3 MAP3K5 human pred
P27448 P27448 Q16539 MARK3 MAPK14 human pred
P27448 P27448 Q9H2K8 MARK3 TAOK3 human pred
P27448 P27448 P31749 MARK3 AKT1 human pred
P27448 P27448 P27448 MARK3 MARK3 human exp
P27448 P27448 P54753 MARK3 EPHB3 human pred
P27448 P27448 Q96F86 MARK3 EDC3 human pred
P27448 P27448 P08069 MARK3 IGF1R human pred
P27448 P27448 Q9UJM3 MARK3 ERRFI1 human pred
P27448 P27448 Q14258 MARK3 TRIM25 human exp
P27448 P27448 Q02156 MARK3 PRKCE human pred
P27448 P27448 O75962 MARK3 TRIO human pred
P27448 P27448 Q13164 MARK3 MAPK7 human pred
P27448 P27448 P42684 MARK3 ABL2 human pred
P27448 P27448 Q9UBF8 MARK3 PI4KB human pred
P27448 P27448 Q53ET0 MARK3 CRTC2 human pred
P27448 P27448 P54764 MARK3 EPHA4 human pred
P27448 P27448 Q96Q42 MARK3 ALS2 human pred
P27448 P27448 Q9H0B6 MARK3 KLC2 human pred
P27448 P27448 P49407 MARK3 ARRB1 human pred
P27448 P27448 P68400 MARK3 CSNK2A1 human pred
P27448 P27448 Q07002 MARK3 CDK18 human pred
P27448 P27448 P63167 MARK3 DYNLL1 human exp,pred
P27448 P27448 P00533 MARK3 EGFR human pred
P27448 P27448 P46937 MARK3 YAP1 human pred
P27448 P27448 O75592 MARK3 MYCBP2 human pred
P27448 P27448 P62633 MARK3 CNBP human exp
P27448 P27448 P24723 MARK3 PRKCH human pred
P27448 P27448 Q9Y5J3 MARK3 HEY1 human exp
P27448 P27448 Q52WX2 MARK3 SBK1 human pred
P27448 P27448 P10636 MARK3 MAPT human exp,pred
P27448 P27448 O00444 MARK3 PLK4 human pred
P27448 P27448 Q05513 MARK3 PRKCZ human pred
P27448 P27448 O14733 MARK3 MAP2K7 human pred
P27448 P27448 P31947 MARK3 SFN human exp,pred
P27448 P27448 O43524 MARK3 FOXO3 human pred
P27448 P27448 Q96ER3 MARK3 SAAL1 human exp
P27448 P27448 Q13627 MARK3 DYRK1A human pred
P27448 P27448 Q15554 MARK3 TERF2 human exp
P27448 P27448 P30307 MARK3 CDC25C human exp,pred
P27448 P27448 Q8TDC3 MARK3 BRSK1 human pred
P27448 P27448 Q13163 MARK3 MAP2K5 human pred
P27448 P27448 Q13153 MARK3 PAK1 human pred
P27448 P27448 Q9UK53 MARK3 ING1 human pred
P27448 P27448 P52907 MARK3 CAPZA1 human exp
P27448 P27448 P11309 MARK3 PIM1 human exp,pred
P27448 P27448 Q00536 MARK3 CDK16 human pred
P27448 P27448 Q6P5Z2 MARK3 PKN3 human pred
P27448 P27448 P29317 MARK3 EPHA2 human pred
P27448 P27448 Q9UKF6 MARK3 CPSF3 human exp
P27448 P27448 Q9Y2U5 MARK3 MAP3K2 human pred
P27448 P27448 Q8N3F8 MARK3 MICALL1 human pred
P27448 P27448 Q9H8H0 MARK3 NOL11 human exp
P27448 P27448 P22455 MARK3 FGFR4 human pred
P27448 P27448 P33981 MARK3 TTK human pred
P27448 P27448 Q9P0L2 MARK3 MARK1 human pred
P27448 P27448 Q9UQM7 MARK3 CAMK2A human pred
P27448 P27448 P54760 MARK3 EPHB4 human pred
P27448 P27448 Q9NPI8 MARK3 FANCF human exp
P27448 P27448 P49815 MARK3 TSC2 human pred
P27448 P27448 Q8IVT5 MARK3 KSR1 human exp,ortho,pred
P27448 P27448 Q99558 MARK3 MAP3K14 human pred
P27448 P27448 Q04759 MARK3 PRKCQ human exp,pred
P27448 P27448 Q86X29 MARK3 LSR human pred
P27448 P27448 Q96TC7 MARK3 RMDN3 human pred
P27448 P27448 P48729 MARK3 CSNK1A1 human pred
P27448 P27448 Q9Y2K2 MARK3 SIK3 human pred
P27448 P27448 O14979 MARK3 HNRNPDL human exp
P27448 P27448 O14757 MARK3 CHEK1 human pred
P27448 P27448 Q9UN71 MARK3 PCDHGB4 human exp
P27448 P27448 P62995 MARK3 TRA2B human pred
P27448 P27448 Q9H0K1 MARK3 SIK2 human pred
P27448 P27448 Q04917 MARK3 YWHAH human exp,ortho,pred
P27448 P27448 P12830 MARK3 CDH1 human exp
P27448 P27448 Q86YC3 MARK3 NRROS human exp
P27448 P27448 Q96RU7 MARK3 TRIB3 human pred
P27448 P27448 Q9UQ88 MARK3 CDK11A human pred
P27448 P27448 Q9BZL6 MARK3 PRKD2 human pred
P27448 P27448 O15530 MARK3 PDPK1 human pred
P27448 P27448 O60285 MARK3 NUAK1 human pred
P27448 P27448 O75478 MARK3 TADA2A human exp
P27448 P27448 O95639 MARK3 CPSF4 human exp
P27448 P27448 Q9UQ35 MARK3 SRRM2 human pred
P27448 P27448 Q6P3R8 MARK3 NEK5 human pred
P27448 P27448 Q8TEP8 MARK3 CEP192 human exp
P27448 P27448 P16234 MARK3 PDGFRA human pred
P27448 P27448 Q6PKG0 MARK3 LARP1 human pred
P27448 P27448 P56524 MARK3 HDAC4 human exp,pred
P27448 P27448 P06493 MARK3 CDK1 human pred
P27448 P27448 O14965 MARK3 AURKA human pred
P27448 P27448 Q5U5Q3 MARK3 MEX3C human exp
P27448 P27448 O60563 MARK3 CCNT1 human pred
P27448 P27448 Q9UJF2 MARK3 RASAL2 human pred
P27448 P27448 Q8NEV4 MARK3 MYO3A human pred
P27448 P27448 P35590 MARK3 TIE1 human pred
P27448 P27448 Q00537 MARK3 CDK17 human pred
P27448 P27448 P18583 MARK3 SON human pred
P27448 P27448 P51812 MARK3 RPS6KA3 human pred
P27448 P27448 Q14738 MARK3 PPP2R5D human pred
P27448 P27448 P49761 MARK3 CLK3 human pred
P27448 P27448 Q92772 MARK3 CDKL2 human pred
P27448 P27448 O60566 MARK3 BUB1B human pred
P27448 P27448 Q96B36 MARK3 AKT1S1 human pred
P27448 P27448 Q9UK80 MARK3 USP21 human exp
P27448 P27448 P41743 MARK3 PRKCI human pred
P27448 P27448 Q9NYV4 MARK3 CDK12 human pred
P27448 P27448 Q8IY84 MARK3 NIM1K human pred
P27448 P27448 Q06187 MARK3 BTK human pred
P27448 P27448 O94921 MARK3 CDK14 human pred
P27448 P27448 P43364 MARK3 MAGEA11 human pred
P27448 P27448 Q8ND76 MARK3 CCNY human pred
P27448 P27448 P78527 MARK3 PRKDC human pred
P27448 P27448 Q9BYG4 MARK3 PARD6G human pred
P27448 P27448 Q9P0K7 MARK3 RAI14 human pred
P27448 P27448 Q9UQL6 MARK3 HDAC5 human exp
P27448 P27448 P14635 MARK3 CCNB1 human pred
P27448 P27448 Q9Y2H1 MARK3 STK38L human pred
P27448 P27448 Q9UQB9 MARK3 AURKC human pred
P27448 P27448 P30305 MARK3 CDC25B human pred
P27448 P27448 Q96NE9 MARK3 FRMD6 human pred
P27448 P27448 P15056 MARK3 BRAF human pred
P27448 P27448 P84103 MARK3 SRSF3 human pred
P27448 P27448 Q8NEB9 MARK3 PIK3C3 human pred
P27448 P27448 Q15287 MARK3 RNPS1 human pred
P27448 P27448 P22681 MARK3 CBL human pred
P27448 P27448 Q99759 MARK3 MAP3K3 human pred
P27448 P27448 Q08881 MARK3 ITK human pred
P27448 P27448 Q9BUB5 MARK3 MKNK1 human pred
P27448 P27448 P07332 MARK3 FES human pred
P27448 P27448 Q9Y4B5 MARK3 MTCL1 human exp
P27448 P27448 P08238 MARK3 HSP90AB1 human pred
P27448 P27448 P23193 MARK3 TCEA1 human pred
P27448 P27448 Q07866 MARK3 KLC1 human pred
P27448 P27448 P31152 MARK3 MAPK4 human pred
P27448 P27448 O96013 MARK3 PAK4 human pred
P27448 P27448 O15151 MARK3 MDM4 human pred
P27448 P27448 Q9UPZ9 MARK3 ICK human pred
P27448 P27448 P49674 MARK3 CSNK1E human pred
P27448 P27448 P10809 MARK3 HSPD1 human pred
P27448 P27448 P51957 MARK3 NEK4 human pred
P27448 P27448 Q96PN8 MARK3 TSSK3 human pred
P27448 P27448 P47756 MARK3 CAPZB human exp
P27448 P27448 Q02241 MARK3 KIF23 human pred
P27448 P27448 Q8NHQ8 MARK3 RASSF8 human pred
P27448 P27448 O75688 MARK3 PPM1B human exp
P27448 P27448 Q86SG6 MARK3 NEK8 human pred
P27448 P27448 P33176 MARK3 KIF5B human pred
P27448 P27448 Q00526 MARK3 CDK3 human pred
P27448 P27448 P41240 MARK3 CSK human pred
P27448 P27448 O00506 MARK3 STK25 human pred
P27448 P27448 P06213 MARK3 INSR human pred
P27448 P27448 Q86X19 MARK3 TMEM17 human exp
P27448 P27448 Q99570 MARK3 PIK3R4 human pred
P27448 P27448 Q9Y2A7 MARK3 NCKAP1 human pred
P27448 P27448 Q92527 MARK3 ANKRD7 human exp
P27448 P27448 Q9H159 MARK3 CDH19 human exp
P27448 P27448 Q96SB4 MARK3 SRPK1 human pred
P27448 P27448 P02766 MARK3 TTR human exp
P27448 P27448 Q13557 MARK3 CAMK2D human pred
P27448 P27448 P32121 MARK3 ARRB2 human pred
P27448 P27448 Q9HBH9 MARK3 MKNK2 human pred
P27448 P27448 P62258 MARK3 YWHAE human exp,ortho,pred
P27448 P27448 P00519 MARK3 ABL1 human pred
P27448 P27448 Q9NYF8 MARK3 BCLAF1 human pred
P27448 P27448 Q9UDY2 MARK3 TJP2 human pred
P27448 P27448 Q9UQ07 MARK3 MOK human pred
P27448 P27448 Q6R327 MARK3 RICTOR human pred
P27448 P27448 Q6PHR2 MARK3 ULK3 human pred
P27448 P27448 P36897 MARK3 TGFBR1 human pred
P27448 P27448 P30304 MARK3 CDC25A human pred
P27448 P27448 Q8WUI4 MARK3 HDAC7 human exp,pred
P27448 P27448 Q7RTN6 MARK3 STRADA human pred
P27448 P27448 Q96RU8 MARK3 TRIB1 human pred
P27448 P27448 P04637 MARK3 TP53 human pred
P27448 P27448 P17612 MARK3 PRKACA human pred
P27448 P27448 Q8N5S9 MARK3 CAMKK1 human pred
P27448 P27448 Q92574 MARK3 TSC1 human pred
P27448 P27448 Q9Y6R4 MARK3 MAP3K4 human pred
P27448 P27448 Q13523 MARK3 PRPF4B human pred
P27448 P27448 Q7L7X3 MARK3 TAOK1 human pred
P27448 P27448 P34947 MARK3 GRK5 human pred
P27448 P27448 Q9C0K7 MARK3 STRADB human pred
P27448 P27448 Q9BXA7 MARK3 TSSK1B human pred
P27448 P27448 Q92974 MARK3 ARHGEF2 human pred
P27448 P27448 Q96L34 MARK3 MARK4 human pred
P27448 P27448 P26038 MARK3 MSN human pred
P27448 P27448 P49841 MARK3 GSK3B human pred
P27448 P27448 P31751 MARK3 AKT2 human pred
P27448 P27448 Q7Z401 MARK3 DENND4A human pred
P27448 P27448 P26045 MARK3 PTPN3 human pred
P27448 P27448 P06241 MARK3 FYN human pred
P27448 P27448 Q14978 MARK3 NOLC1 human pred
P27448 P27448 O94915 MARK3 FRYL human pred
P27448 P27448 P49336 MARK3 CDK8 human pred
P27448 P27448 Q15831 MARK3 STK11 human pred
P27448 P27448 Q13555 MARK3 CAMK2G human pred
P27448 P27448 P06239 MARK3 LCK human pred
P27448 P27448 O75914 MARK3 PAK3 human pred
P27448 P27448 O00273 MARK3 DFFA human pred
P27448 P27448 Q9H1R3 MARK3 MYLK2 human pred
P27448 P27448 O14649 MARK3 KCNK3 human pred
P27448 P27448 Q92997 MARK3 DVL3 human exp
P27448 P27448 Q6ICG6 MARK3 KIAA0930 human pred
P27448 P27448 Q14004 MARK3 CDK13 human pred
P27448 P27448 Q9H4B4 MARK3 PLK3 human pred
P27448 P27448 P57058 MARK3 HUNK human pred
P27448 P27448 P40818 MARK3 USP8 human pred
P27448 P27448 Q16512 MARK3 PKN1 human pred
P27448 P27448 Q86V81 MARK3 ALYREF human exp
P27448 P27448 Q92630 MARK3 DYRK2 human pred
P27448 P27448 Q16890 MARK3 TPD52L1 human pred
P27448 P27448 O75439 MARK3 PMPCB human exp
P27448 P27448 Q13131 MARK3 PRKAA1 human exp,pred
P27448 P27448 Q9BXA6 MARK3 TSSK6 human pred
P27448 P27448 P51817 MARK3 PRKX human pred
P27448 P27448 Q9H093 MARK3 NUAK2 human exp,pred
P27448 P27448 P43405 MARK3 SYK human pred
P27448 P27448 O15111 MARK3 CHUK human pred
P27448 P27448 P46934 MARK3 NEDD4 human pred
P27448 P27448 Q15418 MARK3 RPS6KA1 human pred
P27448 P27448 Q13188 MARK3 STK3 human pred
P27448 P27448 O15075 MARK3 DCLK1 human pred
P27448 P27448 Q9Y4H2 MARK3 IRS2 human pred
P27448 P27448 P05783 MARK3 KRT18 human pred
P27448 P27448 P29322 MARK3 EPHA8 human pred
P27448 P27448 O75643 MARK3 SNRNP200 human pred
P27448 P27448 P49840 MARK3 GSK3A human pred
P27448 P27448 Q9H4L5 MARK3 OSBPL3 human pred
P27448 P27448 Q9Y6E0 MARK3 STK24 human pred
P27448 P27448 P61981 MARK3 YWHAG human exp,ortho,pred
P27448 P27448 P46527 MARK3 CDKN1B human pred
P27448 P27448 O95747 MARK3 OXSR1 human pred
P27448 P27448 Q07912 MARK3 TNK2 human pred
P27448 P27448 P21802 MARK3 FGFR2 human pred
P27448 P27448 P27449 MARK3 ATP6V0C human exp
P27448 P27448 P04049 MARK3 RAF1 human pred
P27448 P27448 Q13043 MARK3 STK4 human pred
P27448 P27448 P32298 MARK3 GRK4 human pred
P27448 P27448 P23528 MARK3 CFL1 human pred
P27448 P27448 P55196 MARK3 AFDN human pred
P27448 P27448 Q15560 MARK3 TCEA2 human exp
P27448 P27448 O75030 MARK3 MITF human exp
P27448 P27448 Q8N3J3 MARK3 C17orf53 human pred
P27448 P27448 P04150 MARK3 NR3C1 human pred
P27448 P27448 Q86X27 MARK3 RALGPS2 human pred
P27448 P27448 Q8TEW0 MARK3 PARD3 human pred
P27448 P27448 O60825 MARK3 PFKFB2 human pred
P27448 P27448 Q92934 MARK3 BAD human pred
P27448 P27448 P21580 MARK3 TNFAIP3 human pred
P27448 P27448 Q6WCQ1 MARK3 MPRIP human pred
P27448 P27448 P62714 MARK3 PPP2CB human exp
P27448 P27448 O43781 MARK3 DYRK3 human pred
P27448 P27448 P27348 MARK3 YWHAQ human exp,pred
P27448 P27448 Q9H270 MARK3 VPS11 human exp
P27448 P27448 P07949 MARK3 RET human pred
P27448 P27448 Q13237 MARK3 PRKG2 human pred
P27448 P27448 Q99959 MARK3 PKP2 human exp
P27448 P27448 Q8N568 MARK3 DCLK2 human pred
P27448 P27448 P42680 MARK3 TEC human pred
P27448 P27448 P16591 MARK3 FER human pred
P27448 P27448 Q86W92 MARK3 PPFIBP1 human pred
P27448 P27448 Q8IWQ3 MARK3 BRSK2 human pred
P27448 P27448 Q8TDM6 MARK3 DLG5 human exp
P27448 P27448 Q5PRF9 MARK3 SAMD4B human pred
P27448 P27448 Q12802 MARK3 AKAP13 human pred
P27448 P27448 P54253 MARK3 ATXN1 human pred
P27448 P27448 P31946 MARK3 YWHAB human exp,ortho,pred
P27448 P27448 Q8WXK3 MARK3 ASB13 human exp
P27448 P27448 P54646 MARK3 PRKAA2 human pred
P27448 P27448 P11137 MARK3 MAP2 human exp
P27448 P27448 Q6A1A2 MARK3 PDPK2P human pred
P27448 P27448 Q5VT25 MARK3 CDC42BPA human pred
P27448 P27448 Q96GD4 MARK3 AURKB human pred
P27448 P27448 O94806 MARK3 PRKD3 human pred
P27448 P27448 O96017 MARK3 CHEK2 human pred
P27448 P27448 P49796 MARK3 RGS3 human pred
P27448 P27448 P53350 MARK3 PLK1 human pred
P27448 P27448 Q14C86 MARK3 GAPVD1 human pred
P27448 P27448 Q13554 MARK3 CAMK2B human pred
P27448 P27448 Q92519 MARK3 TRIB2 human pred
P27448 P27448 Q9NPB6 MARK3 PARD6A human pred
P27448 P27448 Q86UX6 MARK3 STK32C human pred
P27448 P27448 Q9Y4G8 MARK3 RAPGEF2 human pred
P27448 P27448 Q9HC77 MARK3 CENPJ human pred
P27448 P27448 Q9P286 MARK3 PAK5 human pred
P27448 P27448 P49760 MARK3 CLK2 human pred
P27448 P27448 Q9UKV3 MARK3 ACIN1 human pred
P27448 P27448 P63104 MARK3 YWHAZ human exp,ortho,pred
P27448 P27448 Q8N165 MARK3 PDIK1L human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.