Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 36 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P27707 P27707 Q13257 DCK MAD2L1 human pred
P27707 P27707 Q13185 DCK CBX3 human exp
P27707 P27707 P52888 DCK THOP1 human exp
P27707 P27707 O14948 DCK TFEC human exp
P27707 P27707 Q9UMR2 DCK DDX19B human exp
P27707 P27707 P04629 DCK NTRK1 human exp
P27707 P27707 Q9BY43 DCK CHMP4A human exp
P27707 P27707 P22415 DCK USF1 human pred
P27707 P27707 P49902 DCK NT5C2 human pred
P27707 P27707 P61604 DCK HSPE1 human exp
P27707 P27707 Q9Y6K8 DCK AK5 human pred
P27707 P27707 P43487 DCK RANBP1 human exp
P27707 P27707 Q96C19 DCK EFHD2 human exp
P27707 P27707 P32320 DCK CDA human pred
P27707 P27707 Q15717 DCK ELAVL1 human exp
P27707 P27707 Q16854 DCK DGUOK human exp,pred
P27707 P27707 Q9H0P0 DCK NT5C3A human pred
P27707 P27707 Q5EBM0 DCK CMPK2 human pred
P27707 P27707 P27707 DCK DCK human exp,pred
P27707 P27707 P23919 DCK DTYMK human pred
P27707 P27707 P37837 DCK TALDO1 human exp
P27707 P27707 Q16576 DCK RBBP7 human exp
P27707 P27707 P00491 DCK PNP human pred
P27707 P27707 P00813 DCK ADA human pred
P27707 P27707 A0JLT2 DCK MED19 human exp
P27707 P27707 Q8NBJ4 DCK GOLM1 human exp
P27707 P27707 Q8TCD5 DCK NT5C human pred
P27707 P27707 Q9NRG0 DCK CHRAC1 human exp
P27707 P27707 P30520 DCK ADSS human exp
P27707 P27707 Q96M32 DCK AK7 human pred
P27707 P27707 P48443 DCK RXRG human exp
P27707 P27707 P32321 DCK DCTD human pred
P27707 P27707 O75874 DCK IDH1 human exp
P27707 P27707 P04818 DCK TYMS human exp
P27707 P27707 P30085 DCK CMPK1 human pred
P27707 P27707 P20962 DCK PTMS human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.