Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 15 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P31513 P31513 P49326 FMO3 FMO5 human pred
P31513 P31513 P20815 FMO3 CYP3A5 human pred
P31513 P31513 Q99518 FMO3 FMO2 human pred
P31513 P31513 P24462 FMO3 CYP3A7 human pred
P31513 P31513 O43889 FMO3 CREB3 human exp
P31513 P31513 P62258 FMO3 YWHAE human ortho
P31513 P31513 Q16698 FMO3 DECR1 human pred
P31513 P31513 P31512 FMO3 FMO4 human pred
P31513 P31513 P20853 FMO3 CYP2A7 human pred
P31513 P31513 O95336 FMO3 PGLS human ortho
P31513 P31513 Q9H2F3 FMO3 HSD3B7 human ortho
P31513 P31513 P10635 FMO3 CYP2D6 human pred
P31513 P31513 Q01740 FMO3 FMO1 human pred
P31513 P31513 P36537 FMO3 UGT2B10 human pred
P31513 P31513 P08684 FMO3 CYP3A4 human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.