Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 35 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P32302 P32302 P29992 CXCR5 GNA11 human exp
P32302 P32302 Q6PD62 CXCR5 CTR9 human ortho,pred
P32302 P32302 P09341 CXCR5 CXCL1 human pred
P32302 P32302 P02778 CXCR5 CXCL10 human pred
P32302 P32302 P51677 CXCR5 CCR3 human pred
P32302 P32302 Q99731 CXCR5 CCL19 human pred
P32302 P32302 P13501 CXCR5 CCL5 human exp,pred
P32302 P32302 O43927 CXCR5 CXCL13 human exp,pred
P32302 P32302 P61073 CXCR5 CXCR4 human exp
P32302 P32302 Q9UK08 CXCR5 GNG8 human exp
P32302 P32302 P51681 CXCR5 CCR5 human pred
P32302 P32302 P50148 CXCR5 GNAQ human exp
P32302 P32302 Q14344 CXCR5 GNA13 human exp
P32302 P32302 P32246 CXCR5 CCR1 human pred
P32302 P32302 P32302 CXCR5 CXCR5 human exp
P32302 P32302 P13236 CXCR5 CCL4 human exp,pred
P32302 P32302 P01374 CXCR5 LTA human pred
P32302 P32302 Q07325 CXCR5 CXCL9 human pred
P32302 P32302 P10147 CXCR5 CCL3 human exp,pred
P32302 P32302 Q8WV28 CXCR5 BLNK human exp
P32302 P32302 P04899 CXCR5 GNAI2 human exp,pred
P32302 P32302 P80162 CXCR5 CXCL6 human pred
P32302 P32302 P09086 CXCR5 POU2F2 human pred
P32302 P32302 P42830 CXCR5 CXCL5 human pred
P32302 P32302 P02775 CXCR5 PPBP human pred
P32302 P32302 P10720 CXCR5 PF4V1 human pred
P32302 P32302 Q8TAU0 CXCR5 NKX2-3 human pred
P32302 P32302 P19876 CXCR5 CXCL3 human pred
P32302 P32302 O00574 CXCR5 CXCR6 human exp
P32302 P32302 O15467 CXCR5 CCL16 human exp
P32302 P32302 Q16633 CXCR5 POU2AF1 human pred
P32302 P32302 P09471 CXCR5 GNAO1 human exp
P32302 P32302 P16520 CXCR5 GNB3 human exp
P32302 P32302 P19875 CXCR5 CXCL2 human pred
P32302 P32302 P10145 CXCR5 CXCL8 human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.