Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 80 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P35498 P35498 Q9HB14 SCN1A KCNK13 human pred
P35498 P35498 O00555 SCN1A CACNA1A human pred
P35498 P35498 Q9UK17 SCN1A KCND3 human pred
P35498 P35498 O75762 SCN1A TRPA1 human pred
P35498 P35498 Q9NTG1 SCN1A PKDREJ human pred
P35498 P35498 Q14524 SCN1A SCN5A human pred
P35498 P35498 Q8NEC5 SCN1A CATSPER1 human pred
P35498 P35498 O60260 SCN1A PARK2 human pred
P35498 P35498 O94759 SCN1A TRPM2 human pred
P35498 P35498 Q9NZQ8 SCN1A TRPM5 human pred
P35498 P35498 Q9Y5S1 SCN1A TRPV2 human pred
P35498 P35498 P28358 SCN1A HOXD10 human pred
P35498 P35498 O00305 SCN1A CACNB4 human pred
P35498 P35498 Q00975 SCN1A CACNA1B human pred
P35498 P35498 P50993 SCN1A ATP1A2 human pred
P35498 P35498 O43497 SCN1A CACNA1G human pred
P35498 P35498 Q9UBN4 SCN1A TRPC4 human pred
P35498 P35498 P56696 SCN1A KCNQ4 human pred
P35498 P35498 Q8TDN1 SCN1A KCNG4 human pred
P35498 P35498 Q13368 SCN1A MPP3 human exp
P35498 P35498 Q8NER1 SCN1A TRPV1 human pred
P35498 P35498 Q9UL62 SCN1A TRPC5 human pred
P35498 P35498 Q92731 SCN1A ESR2 human exp
P35498 P35498 P18507 SCN1A GABRG2 human pred
P35498 P35498 P25100 SCN1A ADRA1D human pred
P35498 P35498 Q15843 SCN1A NEDD8 human exp
P35498 P35498 Q96QT4 SCN1A TRPM7 human pred
P35498 P35498 Q9P0L9 SCN1A PKD2L1 human pred
P35498 P35498 Q9P0X4 SCN1A CACNA1I human pred
P35498 P35498 Q9HCE6 SCN1A ARHGEF10L human exp
P35498 P35498 Q13507 SCN1A TRPC3 human pred
P35498 P35498 Q9NY46 SCN1A SCN3A human pred
P35498 P35498 Q9H2C0 SCN1A GAN human exp
P35498 P35498 Q86XS8 SCN1A RNF130 human exp
P35498 P35498 Q01668 SCN1A CACNA1D human pred
P35498 P35498 P35499 SCN1A SCN4A human pred
P35498 P35498 P61328 SCN1A FGF12 human exp
P35498 P35498 Q9Y210 SCN1A TRPC6 human pred
P35498 P35498 Q8TD43 SCN1A TRPM4 human pred
P35498 P35498 Q15878 SCN1A CACNA1E human pred
P35498 P35498 Q9NYG8 SCN1A KCNK4 human pred
P35498 P35498 Q14573 SCN1A ITPR3 human pred
P35498 P35498 Q14643 SCN1A ITPR1 human pred
P35498 P35498 P21817 SCN1A RYR1 human pred
P35498 P35498 O94925 SCN1A GLS human pred
P35498 P35498 P48995 SCN1A TRPC1 human pred
P35498 P35498 Q9Y5Y9 SCN1A SCN10A human pred
P35498 P35498 Q13698 SCN1A CACNA1S human pred
P35498 P35498 P53778 SCN1A MAPK12 human pred
P35498 P35498 Q9NR64 SCN1A KLHL1 human pred
P35498 P35498 Q12791 SCN1A KCNMA1 human pred
P35498 P35498 Q92736 SCN1A RYR2 human pred
P35498 P35498 Q96T54 SCN1A KCNK17 human pred
P35498 P35498 Q9UNW9 SCN1A NOVA2 human pred
P35498 P35498 P11230 SCN1A CHRNB1 human pred
P35498 P35498 Q7Z4N2 SCN1A TRPM1 human pred
P35498 P35498 P63252 SCN1A KCNJ2 human pred
P35498 P35498 O00180 SCN1A KCNK1 human pred
P35498 P35498 P0CG48 SCN1A UBC human ortho
P35498 P35498 P48050 SCN1A KCNJ4 human pred
P35498 P35498 Q13563 SCN1A PKD2 human pred
P35498 P35498 Q99250 SCN1A SCN2A human pred
P35498 P35498 P48167 SCN1A GLRB human pred
P35498 P35498 Q9HB15 SCN1A KCNK12 human pred
P35498 P35498 Q9NZM6 SCN1A PKD2L2 human pred
P35498 P35498 Q14571 SCN1A ITPR2 human pred
P35498 P35498 Q07699 SCN1A SCN1B human pred
P35498 P35498 O95180 SCN1A CACNA1H human pred
P35498 P35498 P49768 SCN1A PSEN1 human exp
P35498 P35498 O60939 SCN1A SCN2B human pred
P35498 P35498 Q12879 SCN1A GRIN2A human pred
P35498 P35498 P62158 SCN1A CALM1 human pred
P35498 P35498 Q15413 SCN1A RYR3 human pred
P35498 P35498 Q9UI33 SCN1A SCN11A human pred
P35498 P35498 P01135 SCN1A TGFA human pred
P35498 P35498 Q9NQA5 SCN1A TRPV5 human pred
P35498 P35498 Q15858 SCN1A SCN9A human pred
P35498 P35498 Q13424 SCN1A SNTA1 human exp
P35498 P35498 Q9Y4J8 SCN1A DTNA human pred
P35498 P35498 Q9NZV8 SCN1A KCND2 human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.