Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 79 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P56817 P56817 P09936 BACE1 UCHL1 human pred
P56817 P56817 Q06481 BACE1 APLP2 human pred
P56817 P56817 Q9HCB6 BACE1 SPON1 human pred
P56817 P56817 Q16799 BACE1 RTN1 human pred
P56817 P56817 Q9BXS0 BACE1 COL25A1 human pred
P56817 P56817 P10909 BACE1 CLU human pred
P56817 P56817 P23142 BACE1 FBLN1 human pred
P56817 P56817 O75509 BACE1 TNFRSF21 human pred
P56817 P56817 Q9Y5Z0 BACE1 BACE2 human pred
P56817 P56817 Q9NSC5 BACE1 HOMER3 human pred
P56817 P56817 Q9UNE7 BACE1 STUB1 human exp
P56817 P56817 P61764 BACE1 STXBP1 human pred
P56817 P56817 Q13286 BACE1 CLN3 human pred
P56817 P56817 Q9UJY4 BACE1 GGA2 human exp
P56817 P56817 Q92542 BACE1 NCSTN human exp,pred
P56817 P56817 P08253 BACE1 MMP2 human exp
P56817 P56817 Q14242 BACE1 SELPLG human exp
P56817 P56817 Q92905 BACE1 COPS5 human exp
P56817 P56817 Q07866 BACE1 KLC1 human pred
P56817 P56817 O14618 BACE1 CCS human pred
P56817 P56817 O95415 BACE1 BRI3 human exp
P56817 P56817 P22303 BACE1 ACHE human pred
P56817 P56817 P18669 BACE1 PGAM1 human pred
P56817 P56817 Q6UXB4 BACE1 CLEC4G human ortho
P56817 P56817 O96018 BACE1 APBA3 human pred
P56817 P56817 Q9NZ52 BACE1 GGA3 human exp,pred
P56817 P56817 P00797 BACE1 REN human pred
P56817 P56817 O43736 BACE1 ITM2A human pred
P56817 P56817 P40818 BACE1 USP8 human exp
P56817 P56817 P46459 BACE1 NSF human pred
P56817 P56817 P14091 BACE1 CTSE human pred
P56817 P56817 Q99767 BACE1 APBA2 human pred
P56817 P56817 Q05193 BACE1 DNM1 human pred
P56817 P56817 O75955 BACE1 FLOT1 human exp
P56817 P56817 Q14254 BACE1 FLOT2 human exp
P56817 P56817 P05026 BACE1 ATP1B1 human exp
P56817 P56817 P01011 BACE1 SERPINA3 human pred
P56817 P56817 P09958 BACE1 FURIN human exp,pred
P56817 P56817 O15162 BACE1 PLSCR1 human exp,pred
P56817 P56817 P07550 BACE1 ADRB2 human exp
P56817 P56817 Q92673 BACE1 SORL1 human pred
P56817 P56817 Q8NBP7 BACE1 PCSK9 human exp
P56817 P56817 Q9HCE1 BACE1 MOV10 human exp
P56817 P56817 P56817 BACE1 BACE1 human exp,pred
P56817 P56817 P14136 BACE1 GFAP human pred
P56817 P56817 Q99714 BACE1 HSD17B10 human pred
P56817 P56817 O95197 BACE1 RTN3 human pred
P56817 P56817 Q92945 BACE1 KHSRP human exp
P56817 P56817 Q9NQX7 BACE1 ITM2C human exp,pred
P56817 P56817 P08172 BACE1 CHRM2 human pred
P56817 P56817 P04040 BACE1 CAT human pred
P56817 P56817 Q86VH5 BACE1 LRRTM3 human pred
P56817 P56817 Q92529 BACE1 SHC3 human pred
P56817 P56817 Q92870 BACE1 APBB2 human pred
P56817 P56817 P49768 BACE1 PSEN1 human exp,pred
P56817 P56817 P01023 BACE1 A2M human pred
P56817 P56817 P07339 BACE1 CTSD human pred
P56817 P56817 Q04759 BACE1 PRKCQ human pred
P56817 P56817 O95704 BACE1 APBB3 human pred
P56817 P56817 P02686 BACE1 MBP human pred
P56817 P56817 P30085 BACE1 CMPK1 human exp
P56817 P56817 O75298 BACE1 RTN2 human pred
P56817 P56817 Q96S59 BACE1 RANBP9 human exp
P56817 P56817 P30101 BACE1 PDIA3 human exp
P56817 P56817 P05067 BACE1 APP human exp,pred
P56817 P56817 Q9UK22 BACE1 FBXO2 human exp,ortho
P56817 P56817 P21359 BACE1 NF1 human pred
P56817 P56817 P36544 BACE1 CHRNA7 human pred
P56817 P56817 Q9UJY5 BACE1 GGA1 human exp,pred
P56817 P56817 P51693 BACE1 APLP1 human pred
P56817 P56817 Q9P2D7 BACE1 DNAH1 human pred
P56817 P56817 O94985 BACE1 CLSTN1 human pred
P56817 P56817 P48730 BACE1 CSNK1D human exp
P56817 P56817 P02649 BACE1 APOE human pred
P56817 P56817 Q07954 BACE1 LRP1 human exp,pred
P56817 P56817 P07602 BACE1 PSAP human exp
P56817 P56817 Q02410 BACE1 APBA1 human pred
P56817 P56817 Q9UBU9 BACE1 NXF1 human exp
P56817 P56817 P62937 BACE1 PPIA human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.