Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 27 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P58335 P58335 P58335 ANTXR2 ANTXR2 human exp
P58335 P58335 Q9H461 ANTXR2 FZD8 human pred
P58335 P58335 P08572 ANTXR2 COL4A2 human exp
P58335 P58335 P05362 ANTXR2 ICAM1 human pred
P58335 P58335 P19320 ANTXR2 VCAM1 human pred
P58335 P58335 Q70UQ0 ANTXR2 IKBIP human exp
P58335 P58335 Q9UBU2 ANTXR2 DKK2 human pred
P58335 P58335 Q9H6X2 ANTXR2 ANTXR1 human pred
P58335 P58335 O75581 ANTXR2 LRP6 human exp,pred
P58335 P58335 Q9BXB1 ANTXR2 LGR4 human exp
P58335 P58335 O94907 ANTXR2 DKK1 human pred
P58335 P58335 P04628 ANTXR2 WNT1 human pred
P58335 P58335 P07942 ANTXR2 LAMB1 human exp
P58335 P58335 Q15796 ANTXR2 SMAD2 human exp
P58335 P58335 P62987 ANTXR2 UBA52 human exp
P58335 P58335 P32942 ANTXR2 ICAM3 human pred
P58335 P58335 P56704 ANTXR2 WNT3A human pred
P58335 P58335 Q6ZTN6 ANTXR2 ANKRD13D human exp
P58335 P58335 Q14241 ANTXR2 ELOA human exp
P58335 P58335 P04275 ANTXR2 VWF human pred
P58335 P58335 P53420 ANTXR2 COL4A4 human exp
P58335 P58335 P11047 ANTXR2 LAMC1 human exp
P58335 P58335 P12111 ANTXR2 COL6A3 human pred
P58335 P58335 Q01955 ANTXR2 COL4A3 human exp
P58335 P58335 P20701 ANTXR2 ITGAL human pred
P58335 P58335 P29400 ANTXR2 COL4A5 human exp
P58335 P58335 Q53T59 ANTXR2 HS1BP3 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.