Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 43 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
P78325 P78325 Q9BZ11 ADAM8 ADAM33 human pred
P78325 P78325 Q9UKP5 ADAM8 ADAMTS6 human pred
P78325 P78325 Q9H324 ADAM8 ADAMTS10 human pred
P78325 P78325 P78536 ADAM8 ADAM17 human pred
P78325 P78325 Q9UKQ2 ADAM8 ADAM28 human pred
P78325 P78325 Q9UHI8 ADAM8 ADAMTS1 human pred
P78325 P78325 O43506 ADAM8 ADAM20 human pred
P78325 P78325 Q8TC27 ADAM8 ADAM32 human pred
P78325 P78325 Q8TE57 ADAM8 ADAMTS16 human pred
P78325 P78325 Q8WXS8 ADAM8 ADAMTS14 human pred
P78325 P78325 P01033 ADAM8 TIMP1 human pred
P78325 P78325 Q9UKF5 ADAM8 ADAM29 human pred
P78325 P78325 P19883 ADAM8 FST human exp
P78325 P78325 Q9Y3Q7 ADAM8 ADAM18 human pred
P78325 P78325 P41161 ADAM8 ETV5 human exp
P78325 P78325 Q9UKJ8 ADAM8 ADAM21 human pred
P78325 P78325 Q8TE56 ADAM8 ADAMTS17 human pred
P78325 P78325 Q9UKP4 ADAM8 ADAMTS7 human pred
P78325 P78325 Q9UP79 ADAM8 ADAMTS8 human pred
P78325 P78325 Q9H2U9 ADAM8 ADAM7 human pred
P78325 P78325 Q8TE59 ADAM8 ADAMTS19 human pred
P78325 P78325 O95633 ADAM8 FSTL3 human exp
P78325 P78325 O43184 ADAM8 ADAM12 human pred
P78325 P78325 Q8TE60 ADAM8 ADAMTS18 human pred
P78325 P78325 Q14242 ADAM8 SELPLG human exp
P78325 P78325 Q76LX8 ADAM8 ADAMTS13 human pred
P78325 P78325 Q99965 ADAM8 ADAM2 human pred
P78325 P78325 P29144 ADAM8 TPP2 human exp
P78325 P78325 Q9UNA0 ADAM8 ADAMTS5 human pred
P78325 P78325 Q13443 ADAM8 ADAM9 human pred
P78325 P78325 Q9UKF2 ADAM8 ADAM30 human pred
P78325 P78325 Q9P0K1 ADAM8 ADAM22 human pred
P78325 P78325 Q13444 ADAM8 ADAM15 human pred
P78325 P78325 O75077 ADAM8 ADAM23 human pred
P78325 P78325 P59510 ADAM8 ADAMTS20 human pred
P78325 P78325 Q8TE58 ADAM8 ADAMTS15 human pred
P78325 P78325 O75078 ADAM8 ADAM11 human pred
P78325 P78325 Q9H013 ADAM8 ADAM19 human pred
P78325 P78325 O15204 ADAM8 ADAMDEC1 human pred
P78325 P78325 O95450 ADAM8 ADAMTS2 human pred
P78325 P78325 P58397 ADAM8 ADAMTS12 human pred
P78325 P78325 Q9P2N4 ADAM8 ADAMTS9 human pred
P78325 P78325 O75173 ADAM8 ADAMTS4 human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.