Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 19 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q03013 Q03013 Q5T3J3 GSTM4 LRIF1 human exp
Q03013 Q03013 Q9Y3C7 GSTM4 MED31 human exp
Q03013 Q03013 Q04724 GSTM4 TLE1 human exp
Q03013 Q03013 P28161 GSTM4 GSTM2 human exp,pred
Q03013 Q03013 Q8IXH7 GSTM4 NELFCD human exp
Q03013 Q03013 Q03013 GSTM4 GSTM4 human exp,pred
Q03013 Q03013 O95817 GSTM4 BAG3 human exp
Q03013 Q03013 P46439 GSTM4 GSTM5 human exp,pred
Q03013 Q03013 Q13432 GSTM4 UNC119 human exp
Q03013 Q03013 P51693 GSTM4 APLP1 human exp
Q03013 Q03013 P04637 GSTM4 TP53 human exp
Q03013 Q03013 P09488 GSTM4 GSTM1 human pred
Q03013 Q03013 P21266 GSTM4 GSTM3 human exp,pred
Q03013 Q03013 P30712 GSTM4 - human pred
Q03013 Q03013 Q96ID5 GSTM4 IGSF21 human exp
Q03013 Q03013 P09211 GSTM4 GSTP1 human pred
Q03013 Q03013 Q5UIP0 GSTM4 RIF1 human exp
Q03013 Q03013 Q05516 GSTM4 ZBTB16 human exp
Q03013 Q03013 Q04727 GSTM4 TLE4 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.