Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 13 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q14320 Q14320 Q01844 FAM50A EWSR1 human exp
Q14320 Q14320 Q02078 FAM50A MEF2A human exp
Q14320 Q14320 P01100 FAM50A FOS human exp
Q14320 Q14320 P55317 FAM50A FOXA1 human exp
Q14320 Q14320 Q9HCE1 FAM50A MOV10 human exp
Q14320 Q14320 Q9H944 FAM50A MED20 human exp
Q14320 Q14320 Q9NQ48 FAM50A LZTFL1 human pred
Q14320 Q14320 P05067 FAM50A APP human exp
Q14320 Q14320 Q9UBU9 FAM50A NXF1 human exp
Q14320 Q14320 Q9NPJ6 FAM50A MED4 human exp
Q14320 Q14320 Q15370 FAM50A ELOB human exp
Q14320 Q14320 Q86W50 FAM50A METTL16 human exp
Q14320 Q14320 P24723 FAM50A PRKCH human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.