Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 25 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q15915 Q15915 P02686 ZIC1 MBP human pred
Q15915 Q15915 Q9BRP0 ZIC1 OVOL2 human pred
Q15915 Q15915 Q96T25 ZIC1 ZIC5 human pred
Q15915 Q15915 Q92858 ZIC1 ATOH1 human pred
Q15915 Q15915 P10071 ZIC1 GLI3 human exp,pred
Q15915 Q15915 Q9UJW2 ZIC1 TINAG human pred
Q15915 Q15915 O95409 ZIC1 ZIC2 human pred
Q15915 Q15915 Q9Y219 ZIC1 JAG2 human pred
Q15915 Q15915 Q92793 ZIC1 CREBBP human pred
Q15915 Q15915 P12644 ZIC1 BMP4 human pred
Q15915 Q15915 P10070 ZIC1 GLI2 human exp,ortho,pred
Q15915 Q15915 P32243 ZIC1 OTX2 human pred
Q15915 Q15915 P57775 ZIC1 FBXW4 human pred
Q15915 Q15915 P08151 ZIC1 GLI1 human exp,pred
Q15915 Q15915 P12755 ZIC1 SKI human pred
Q15915 Q15915 P22888 ZIC1 LHCGR human pred
Q15915 Q15915 O15344 ZIC1 MID1 human pred
Q15915 Q15915 O00548 ZIC1 DLL1 human pred
Q15915 Q15915 Q9HBZ2 ZIC1 ARNT2 human pred
Q15915 Q15915 Q9H2X0 ZIC1 CHRD human pred
Q15915 Q15915 Q9Y297 ZIC1 BTRC human pred
Q15915 Q15915 Q5VUG0 ZIC1 SFMBT2 human pred
Q15915 Q15915 P37058 ZIC1 HSD17B3 human pred
Q15915 Q15915 O60481 ZIC1 ZIC3 human pred
Q15915 Q15915 Q99684 ZIC1 GFI1 human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.