Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 37 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q29974 Q29974 Q6ICR9 HLA-DRB1 HLA-DMA human exp
Q29974 Q29974 Q14534 HLA-DRB1 SQLE human exp
Q29974 Q29974 Q29974 HLA-DRB1 HLA-DRB1 human exp
Q29974 Q29974 Q30154 HLA-DRB1 HLA-DRB5 human exp
Q29974 Q29974 P14618 HLA-DRB1 PKM human exp
Q29974 Q29974 Q9H6D8 HLA-DRB1 FNDC4 human exp
Q29974 Q29974 O95476 HLA-DRB1 CTDNEP1 human exp
Q29974 Q29974 Q8NC42 HLA-DRB1 RNF149 human exp
Q29974 Q29974 P43357 HLA-DRB1 MAGEA3 human exp
Q29974 Q29974 P62258 HLA-DRB1 YWHAE human exp
Q29974 Q29974 P28067 HLA-DRB1 HLA-DMA human exp
Q29974 Q29974 P50995 HLA-DRB1 ANXA11 human exp
Q29974 Q29974 P23229 HLA-DRB1 ITGA6 human exp
Q29974 Q29974 P79483 HLA-DRB1 HLA-DRB3 human exp
Q29974 Q29974 Q8IUH5 HLA-DRB1 ZDHHC17 human exp
Q29974 Q29974 Q8IZA0 HLA-DRB1 KIAA0319L human exp
Q29974 Q29974 Q9NX62 HLA-DRB1 IMPAD1 human exp
Q29974 Q29974 P78358 HLA-DRB1 CTAG1A human exp
Q29974 Q29974 Q9NZJ5 HLA-DRB1 EIF2AK3 human exp
Q29974 Q29974 Q58DX5 HLA-DRB1 NAALADL2 human exp
Q29974 Q29974 Q9BV81 HLA-DRB1 EMC6 human exp
Q29974 Q29974 Q96KN2 HLA-DRB1 CNDP1 human exp
Q29974 Q29974 P11142 HLA-DRB1 HSPA8 human exp
Q29974 Q29974 P19474 HLA-DRB1 TRIM21 human exp
Q29974 Q29974 P55072 HLA-DRB1 VCP human exp
Q29974 Q29974 P07900 HLA-DRB1 HSP90AA1 human exp
Q29974 Q29974 P01903 HLA-DRB1 HLA-DRA human exp
Q29974 Q29974 P08238 HLA-DRB1 HSP90AB1 human exp
Q29974 Q29974 Q8TCT1 HLA-DRB1 PHOSPHO1 human exp
Q29974 Q29974 P11836 HLA-DRB1 MS4A1 human exp
Q29974 Q29974 O95754 HLA-DRB1 SEMA4F human exp
Q29974 Q29974 Q8WVV5 HLA-DRB1 BTN2A2 human exp
Q29974 Q29974 Q9NRU3 HLA-DRB1 CNNM1 human exp
Q29974 Q29974 Q13370 HLA-DRB1 PDE3B human exp
Q29974 Q29974 P20774 HLA-DRB1 OGN human exp
Q29974 Q29974 P05026 HLA-DRB1 ATP1B1 human exp
Q29974 Q29974 Q8TCQ1 HLA-DRB1 MARCH1 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.