Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 11 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q5T0L3 Q5T0L3 P50747 SPATA46 HLCS human exp
Q5T0L3 Q5T0L3 Q93062 SPATA46 RBPMS human exp
Q5T0L3 Q5T0L3 Q9Y343 SPATA46 SNX24 human exp
Q5T0L3 Q5T0L3 P48729 SPATA46 CSNK1A1 human exp
Q5T0L3 Q5T0L3 Q99685 SPATA46 MGLL human exp
Q5T0L3 Q5T0L3 P05067 SPATA46 APP human exp
Q5T0L3 Q5T0L3 Q14C86 SPATA46 GAPVD1 human exp
Q5T0L3 Q5T0L3 O15151 SPATA46 MDM4 human exp
Q5T0L3 Q5T0L3 A2RUC4 SPATA46 TYW5 human exp
Q5T0L3 Q5T0L3 Q96GE4 SPATA46 CEP95 human exp
Q5T0L3 Q5T0L3 Q15834 SPATA46 CCDC85B human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.