Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 15 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q5T6V5 Q5T6V5 Q8IW45 C9orf64 NAXD human exp
Q5T6V5 Q5T6V5 Q15717 C9orf64 ELAVL1 human exp
Q5T6V5 Q5T6V5 Q9UGP5 C9orf64 POLL human exp
Q5T6V5 Q5T6V5 Q9HBL8 C9orf64 NMRAL1 human exp
Q5T6V5 Q5T6V5 Q9BY32 C9orf64 ITPA human exp
Q5T6V5 Q5T6V5 Q12882 C9orf64 DPYD human exp
Q5T6V5 Q5T6V5 P14618 C9orf64 PKM human exp
Q5T6V5 Q5T6V5 P0DN37 C9orf64 PPIAL4G human exp
Q5T6V5 Q5T6V5 Q9GZT8 C9orf64 NIF3L1 human exp
Q5T6V5 Q5T6V5 Q15843 C9orf64 NEDD8 human exp
Q5T6V5 Q5T6V5 P04629 C9orf64 NTRK1 human exp
Q5T6V5 Q5T6V5 P07954 C9orf64 FH human exp
Q5T6V5 Q5T6V5 Q06136 C9orf64 KDSR human ortho
Q5T6V5 Q5T6V5 Q4G0W2 C9orf64 DUSP28 human exp
Q5T6V5 Q5T6V5 Q9H596 C9orf64 DUSP21 human exp

Return to Output Options

Return to top

Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.