Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 10 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q6NVH7 Q6NVH7 Q06609 SWSAP1 RAD51 human exp
Q6NVH7 Q6NVH7 P0CG47 SWSAP1 UBB human exp
Q6NVH7 Q6NVH7 O14556 SWSAP1 GAPDHS human exp
Q6NVH7 Q6NVH7 O75771 SWSAP1 RAD51D human exp
Q6NVH7 Q6NVH7 P01023 SWSAP1 A2M human exp
Q6NVH7 Q6NVH7 Q19AV6 SWSAP1 ZSWIM7 human exp
Q6NVH7 Q6NVH7 O15496 SWSAP1 PLA2G10 human exp
Q6NVH7 Q6NVH7 O43542 SWSAP1 XRCC3 human exp
Q6NVH7 Q6NVH7 O15315 SWSAP1 RAD51B human exp
Q6NVH7 Q6NVH7 O43502 SWSAP1 RAD51C human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.