Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 16 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q6PIJ6 Q6PIJ6 P42684 FBXO38 ABL2 human exp
Q6PIJ6 Q6PIJ6 Q9HCE1 FBXO38 MOV10 human exp
Q6PIJ6 Q6PIJ6 O15355 FBXO38 PPM1G human exp
Q6PIJ6 Q6PIJ6 P34897 FBXO38 SHMT2 human exp
Q6PIJ6 Q6PIJ6 P63208 FBXO38 SKP1 human exp
Q6PIJ6 Q6PIJ6 Q93009 FBXO38 USP7 human exp
Q6PIJ6 Q6PIJ6 P63167 FBXO38 DYNLL1 human exp
Q6PIJ6 Q6PIJ6 O75840 FBXO38 KLF7 human exp,pred
Q6PIJ6 Q6PIJ6 P08238 FBXO38 HSP90AB1 human exp
Q6PIJ6 Q6PIJ6 Q06587 FBXO38 RING1 human exp
Q6PIJ6 Q6PIJ6 Q16543 FBXO38 CDC37 human exp
Q6PIJ6 Q6PIJ6 O94993 FBXO38 SOX30 human exp
Q6PIJ6 Q6PIJ6 P07900 FBXO38 HSP90AA1 human exp
Q6PIJ6 Q6PIJ6 P05067 FBXO38 APP human exp
Q6PIJ6 Q6PIJ6 Q9UBU9 FBXO38 NXF1 human exp
Q6PIJ6 Q6PIJ6 Q08830 FBXO38 FGL1 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.