Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 14 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q6PK04 Q6PK04 Q9UGY1 CCDC137 NOL12 human exp
Q6PK04 Q6PK04 P50914 CCDC137 RPL14 human exp
Q6PK04 Q6PK04 Q16666 CCDC137 IFI16 human exp
Q6PK04 Q6PK04 O00567 CCDC137 NOP56 human exp
Q6PK04 Q6PK04 Q9BZS1 CCDC137 FOXP3 human ortho
Q6PK04 Q6PK04 P56134 CCDC137 ATP5J2 human exp
Q6PK04 Q6PK04 Q13368 CCDC137 MPP3 human exp
Q6PK04 Q6PK04 Q00839 CCDC137 HNRNPU human exp
Q6PK04 Q6PK04 P41218 CCDC137 MNDA human exp
Q6PK04 Q6PK04 Q15554 CCDC137 TERF2 human exp
Q6PK04 Q6PK04 P06748 CCDC137 NPM1 human exp
Q6PK04 Q6PK04 Q9UPE1 CCDC137 SRPK3 human exp
Q6PK04 Q6PK04 P62917 CCDC137 RPL8 human exp
Q6PK04 Q6PK04 Q04917 CCDC137 YWHAH human ortho

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.