Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 10 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q6UWW0 Q6UWW0 Q9NV35 LCN15 NUDT15 human exp
Q6UWW0 Q6UWW0 Q6NS38 LCN15 ALKBH2 human exp
Q6UWW0 Q6UWW0 Q13459 LCN15 MYO9B human exp
Q6UWW0 Q6UWW0 A5A3E0 LCN15 POTEF human exp
Q6UWW0 Q6UWW0 Q6UXE8 LCN15 BTNL3 human pred
Q6UWW0 Q6UWW0 Q8WYN0 LCN15 ATG4A human exp
Q6UWW0 Q6UWW0 Q99856 LCN15 ARID3A human exp
Q6UWW0 Q6UWW0 Q8TF46 LCN15 DIS3L human exp
Q6UWW0 Q6UWW0 Q7Z333 LCN15 SETX human exp
Q6UWW0 Q6UWW0 Q9H977 LCN15 WDR54 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.