Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 5 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q7Z5W3 Q7Z5W3 Q15717 BCDIN3D ELAVL1 human exp
Q7Z5W3 Q7Z5W3 Q13618 BCDIN3D CUL3 human exp
Q7Z5W3 Q7Z5W3 Q86VU5 BCDIN3D COMTD1 human pred
Q7Z5W3 Q7Z5W3 Q6ZN57 BCDIN3D ZFP2 human exp
Q7Z5W3 Q7Z5W3 Q7Z5W3 BCDIN3D BCDIN3D human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.