Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 9 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q86VQ1 Q86VQ1 O14980 GLCCI1 XPO1 human exp
Q86VQ1 Q86VQ1 Q9UK41 GLCCI1 VPS28 human exp
Q86VQ1 Q86VQ1 P63167 GLCCI1 DYNLL1 human exp
Q86VQ1 Q86VQ1 Q13627 GLCCI1 DYRK1A human exp
Q86VQ1 Q86VQ1 Q9Y463 GLCCI1 DYRK1B human exp
Q86VQ1 Q86VQ1 Q9P2P5 GLCCI1 HECW2 human exp
Q86VQ1 Q86VQ1 Q7L0X2 GLCCI1 ERICH6 human exp
Q86VQ1 Q86VQ1 Q8WV44 GLCCI1 TRIM41 human exp
Q86VQ1 Q86VQ1 P61962 GLCCI1 DCAF7 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.