Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 60 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q86Y56 Q86Y56 P00533 - EGFR human exp
Q86Y56 Q86Y56 Q9NVT9 - ARMC1 human exp
Q86Y56 Q86Y56 Q86VU5 - COMTD1 human exp
Q86Y56 Q86Y56 Q15910 - EZH2 human exp
Q86Y56 Q86Y56 P28482 - MAPK1 human exp
Q86Y56 Q86Y56 Q8TAT6 - NPLOC4 human exp
Q86Y56 Q86Y56 Q96GG9 - DCUN1D1 human exp
Q86Y56 Q86Y56 Q14738 - PPP2R5D human exp
Q86Y56 Q86Y56 Q96QU8 - XPO6 human exp
Q86Y56 Q86Y56 O76071 - CIAO1 human exp
Q86Y56 Q86Y56 Q9BRZ2 - TRIM56 human pred
Q86Y56 Q86Y56 Q05048 - CSTF1 human exp
Q86Y56 Q86Y56 O75365 - PTP4A3 human exp
Q86Y56 Q86Y56 Q9H444 - CHMP4B human exp
Q86Y56 Q86Y56 P27105 - STOM human exp
Q86Y56 Q86Y56 Q9Y2Q3 - GSTK1 human exp
Q86Y56 Q86Y56 Q06210 - GFPT1 human exp
Q86Y56 Q86Y56 Q8TDB6 - DTX3L human pred
Q86Y56 Q86Y56 P21333 - FLNA human exp
Q86Y56 Q86Y56 Q96T60 - PNKP human exp
Q86Y56 Q86Y56 Q9UBU9 - NXF1 human exp
Q86Y56 Q86Y56 P54727 - RAD23B human exp
Q86Y56 Q86Y56 O94766 - B3GAT3 human exp
Q86Y56 Q86Y56 Q99689 - FEZ1 human exp
Q86Y56 Q86Y56 Q9HAW0 - BRF2 human exp
Q86Y56 Q86Y56 Q9Y4K3 - TRAF6 human pred
Q86Y56 Q86Y56 O00264 - PGRMC1 human exp
Q86Y56 Q86Y56 P30154 - PPP2R1B human exp
Q86Y56 Q86Y56 P62330 - ARF6 human exp
Q86Y56 Q86Y56 P31350 - RRM2 human exp
Q86Y56 Q86Y56 Q9HCE1 - MOV10 human exp
Q86Y56 Q86Y56 P43360 - MAGEA6 human exp
Q86Y56 Q86Y56 Q15714 - TSC22D1 human exp
Q86Y56 Q86Y56 Q02297 - NRG1 human exp
Q86Y56 Q86Y56 Q9Y5J5 - PHLDA3 human exp
Q86Y56 Q86Y56 Q13418 - ILK human exp
Q86Y56 Q86Y56 Q86Y56 - - human exp
Q86Y56 Q86Y56 P21589 - NT5E human exp
Q86Y56 Q86Y56 O95274 - LYPD3 human exp
Q86Y56 Q86Y56 P30153 - PPP2R1A human exp
Q86Y56 Q86Y56 Q86VZ1 - P2RY8 human exp
Q86Y56 Q86Y56 Q9UBP6 - METTL1 human exp
Q86Y56 Q86Y56 Q5M7Z0 - RNFT1 human pred
Q86Y56 Q86Y56 Q05516 - ZBTB16 human exp
Q86Y56 Q86Y56 P25098 - GRK2 human exp
Q86Y56 Q86Y56 P49662 - CASP4 human exp
Q86Y56 Q86Y56 Q9HC98 - NEK6 human exp
Q86Y56 Q86Y56 P52597 - HNRNPF human exp
Q86Y56 Q86Y56 P61158 - ACTR3 human exp
Q86Y56 Q86Y56 O00422 - SAP18 human exp
Q86Y56 Q86Y56 P35613 - BSG human exp
Q86Y56 Q86Y56 Q13572 - ITPK1 human exp
Q86Y56 Q86Y56 P01106 - MYC human exp
Q86Y56 Q86Y56 Q96AY3 - FKBP10 human exp
Q86Y56 Q86Y56 Q13616 - CUL1 human pred
Q86Y56 Q86Y56 P10586 - PTPRF human exp
Q86Y56 Q86Y56 P53350 - PLK1 human exp
Q86Y56 Q86Y56 Q9GZS0 - DNAI2 human exp
Q86Y56 Q86Y56 Q9Y5V3 - MAGED1 human exp
Q86Y56 Q86Y56 P04629 - NTRK1 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.