Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 21 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q8IVA1 Q8IVA1 P08754 PCP2 GNAI3 human exp
Q8IVA1 Q8IVA1 P28827 PCP2 PTPRM human pred
Q8IVA1 Q8IVA1 Q9H9E3 PCP2 COG4 human ortho
Q8IVA1 Q8IVA1 P09471 PCP2 GNAO1 human ortho,pred
Q8IVA1 Q8IVA1 Q9H6F2 PCP2 TMEM38A human exp
Q8IVA1 Q8IVA1 Q9Y283 PCP2 INVS human ortho
Q8IVA1 Q8IVA1 P37058 PCP2 HSD17B3 human exp
Q8IVA1 Q8IVA1 Q9NSP4 PCP2 CENPM human exp
Q8IVA1 Q8IVA1 Q5W186 PCP2 CST9 human exp
Q8IVA1 Q8IVA1 Q02241 PCP2 KIF23 human ortho
Q8IVA1 Q8IVA1 P14923 PCP2 JUP human ortho
Q8IVA1 Q8IVA1 P62258 PCP2 YWHAE human ortho
Q8IVA1 Q8IVA1 P10153 PCP2 RNASE2 human exp
Q8IVA1 Q8IVA1 P12814 PCP2 ACTN1 human ortho
Q8IVA1 Q8IVA1 O95817 PCP2 BAG3 human exp
Q8IVA1 Q8IVA1 Q5JWF2 PCP2 GNAS human ortho
Q8IVA1 Q8IVA1 P35222 PCP2 CTNNB1 human ortho
Q8IVA1 Q8IVA1 P04899 PCP2 GNAI2 human ortho
Q8IVA1 Q8IVA1 P35221 PCP2 CTNNA1 human ortho
Q8IVA1 Q8IVA1 P10515 PCP2 DLAT human ortho
Q8IVA1 Q8IVA1 Q9UK41 PCP2 VPS28 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.