Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 24 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q8IZE3 Q8IZE3 P16070 SCYL3 CD44 human exp,pred
Q8IZE3 Q8IZE3 Q99757 SCYL3 TXN2 human exp
Q8IZE3 Q8IZE3 P26038 SCYL3 MSN human pred
Q8IZE3 Q8IZE3 P25445 SCYL3 FAS human pred
Q8IZE3 Q8IZE3 Q96DB2 SCYL3 HDAC11 human exp
Q8IZE3 Q8IZE3 Q9H0R8 SCYL3 GABARAPL1 human exp
Q8IZE3 Q8IZE3 Q13464 SCYL3 ROCK1 human pred
Q8IZE3 Q8IZE3 P07332 SCYL3 FES human pred
Q8IZE3 Q8IZE3 O14980 SCYL3 XPO1 human exp
Q8IZE3 Q8IZE3 P56180 SCYL3 TPTE human exp
Q8IZE3 Q8IZE3 P23508 SCYL3 MCC human pred
Q8IZE3 Q8IZE3 Q96LK0 SCYL3 CEP19 human exp
Q8IZE3 Q8IZE3 Q8WX93 SCYL3 PALLD human pred
Q8IZE3 Q8IZE3 P32942 SCYL3 ICAM3 human pred
Q8IZE3 Q8IZE3 P51124 SCYL3 GZMM human pred
Q8IZE3 Q8IZE3 Q15599 SCYL3 SLC9A3R2 human pred
Q8IZE3 Q8IZE3 Q68G74 SCYL3 LHX8 human exp
Q8IZE3 Q8IZE3 Q86X19 SCYL3 TMEM17 human exp
Q8IZE3 Q8IZE3 Q9P0N5 SCYL3 TMEM216 human exp
Q8IZE3 Q8IZE3 P00533 SCYL3 EGFR human pred
Q8IZE3 Q8IZE3 P35240 SCYL3 NF2 human pred
Q8IZE3 Q8IZE3 O14745 SCYL3 SLC9A3R1 human pred
Q8IZE3 Q8IZE3 P15311 SCYL3 EZR human exp
Q8IZE3 Q8IZE3 P32004 SCYL3 L1CAM human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.