Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 20 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q8IZJ1 Q8IZJ1 Q8IZJ1 UNC5B UNC5B human ortho,pred
Q8IZJ1 Q8IZJ1 O95631 UNC5B NTN1 human exp,ortho,pred
Q8IZJ1 Q8IZJ1 Q6ZN44 UNC5B UNC5A human pred
Q8IZJ1 Q8IZJ1 Q99490 UNC5B AGAP2 human ortho
Q8IZJ1 Q8IZJ1 P43146 UNC5B DCC human pred
Q8IZJ1 Q8IZJ1 Q92859 UNC5B NEO1 human exp
Q8IZJ1 Q8IZJ1 P09486 UNC5B SPARC human pred
Q8IZJ1 Q8IZJ1 Q8TCG1 UNC5B CIP2A human exp
Q8IZJ1 Q8IZJ1 Q9P0N5 UNC5B TMEM216 human exp
Q8IZJ1 Q8IZJ1 P53355 UNC5B DAPK1 human exp,ortho,pred
Q8IZJ1 Q8IZJ1 Q6UXZ4 UNC5B UNC5D human pred
Q8IZJ1 Q8IZJ1 Q86X19 UNC5B TMEM17 human exp
Q8IZJ1 Q8IZJ1 Q96JM4 UNC5B LRRIQ1 human exp
Q8IZJ1 Q8IZJ1 P23258 UNC5B TUBG1 human exp
Q8IZJ1 Q8IZJ1 O95185 UNC5B UNC5C human pred
Q8IZJ1 Q8IZJ1 P30153 UNC5B PPP2R1A human ortho
Q8IZJ1 Q8IZJ1 P30154 UNC5B PPP2R1B human exp,ortho
Q8IZJ1 Q8IZJ1 P04629 UNC5B NTRK1 human exp
Q8IZJ1 Q8IZJ1 P67775 UNC5B PPP2CA human exp,ortho
Q8IZJ1 Q8IZJ1 Q9NP85 UNC5B NPHS2 human ortho

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.