Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 109 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q8NBP7 Q8NBP7 Q96PK6 PCSK9 RBM14 human pred
Q8NBP7 Q8NBP7 P98155 PCSK9 VLDLR human pred
Q8NBP7 Q8NBP7 P53621 PCSK9 COPA human pred
Q8NBP7 Q8NBP7 O14939 PCSK9 PLD2 human pred
Q8NBP7 Q8NBP7 O14967 PCSK9 CLGN human exp
Q8NBP7 Q8NBP7 Q53H12 PCSK9 AGK human exp
Q8NBP7 Q8NBP7 P35606 PCSK9 COPB2 human pred
Q8NBP7 Q8NBP7 Q6NXE6 PCSK9 ARMC6 human exp
Q8NBP7 Q8NBP7 O95727 PCSK9 CRTAM human pred
Q8NBP7 Q8NBP7 Q9HCK4 PCSK9 ROBO2 human pred
Q8NBP7 Q8NBP7 Q92900 PCSK9 UPF1 human ortho
Q8NBP7 Q8NBP7 Q15293 PCSK9 RCN1 human exp
Q8NBP7 Q8NBP7 P08253 PCSK9 MMP2 human exp
Q8NBP7 Q8NBP7 O94817 PCSK9 ATG12 human pred
Q8NBP7 Q8NBP7 Q712K3 PCSK9 UBE2R2 human ortho
Q8NBP7 Q8NBP7 Q9UBU9 PCSK9 NXF1 human exp
Q8NBP7 Q8NBP7 Q9Y5K6 PCSK9 CD2AP human pred
Q8NBP7 Q8NBP7 P01185 PCSK9 AVP human pred
Q8NBP7 Q8NBP7 Q5SW96 PCSK9 LDLRAP1 human pred
Q8NBP7 Q8NBP7 P10586 PCSK9 PTPRF human pred
Q8NBP7 Q8NBP7 Q92824 PCSK9 PCSK5 human pred
Q8NBP7 Q8NBP7 Q9UNE7 PCSK9 STUB1 human exp
Q8NBP7 Q8NBP7 P17948 PCSK9 FLT1 human pred
Q8NBP7 Q8NBP7 Q03426 PCSK9 MVK human pred
Q8NBP7 Q8NBP7 P02649 PCSK9 APOE human pred
Q8NBP7 Q8NBP7 Q9H0E7 PCSK9 USP44 human pred
Q8NBP7 Q8NBP7 O75746 PCSK9 SLC25A12 human exp
Q8NBP7 Q8NBP7 O60667 PCSK9 FCMR human pred
Q8NBP7 Q8NBP7 Q8IXI2 PCSK9 RHOT1 human exp
Q8NBP7 Q8NBP7 Q12933 PCSK9 TRAF2 human exp
Q8NBP7 Q8NBP7 O75553 PCSK9 DAB1 human pred
Q8NBP7 Q8NBP7 P09958 PCSK9 FURIN human pred
Q8NBP7 Q8NBP7 Q9BY67 PCSK9 CADM1 human pred
Q8NBP7 Q8NBP7 Q8IV16 PCSK9 GPIHBP1 human pred
Q8NBP7 Q8NBP7 P16581 PCSK9 SELE human pred
Q8NBP7 Q8NBP7 P63208 PCSK9 SKP1 human pred
Q8NBP7 Q8NBP7 Q9Y279 PCSK9 VSIG4 human pred
Q8NBP7 Q8NBP7 Q9UBS4 PCSK9 DNAJB11 human exp
Q8NBP7 Q8NBP7 P37268 PCSK9 FDFT1 human pred
Q8NBP7 Q8NBP7 Q8NBP7 PCSK9 PCSK9 human exp
Q8NBP7 Q8NBP7 P01130 PCSK9 LDLR human exp,pred
Q8NBP7 Q8NBP7 P10747 PCSK9 CD28 human pred
Q8NBP7 Q8NBP7 P56817 PCSK9 BACE1 human exp
Q8NBP7 Q8NBP7 Q16584 PCSK9 MAP3K11 human pred
Q8NBP7 Q8NBP7 O14931 PCSK9 NCR3 human pred
Q8NBP7 Q8NBP7 Q9NYU2 PCSK9 UGGT1 human exp
Q8NBP7 Q8NBP7 Q5VST9 PCSK9 OBSCN human pred
Q8NBP7 Q8NBP7 Q9UBX3 PCSK9 SLC25A10 human exp
Q8NBP7 Q8NBP7 O43639 PCSK9 NCK2 human pred
Q8NBP7 Q8NBP7 O14735 PCSK9 CDIPT human exp
Q8NBP7 Q8NBP7 O00468 PCSK9 AGRN human pred
Q8NBP7 Q8NBP7 P04216 PCSK9 THY1 human pred
Q8NBP7 Q8NBP7 Q15375 PCSK9 EPHA7 human pred
Q8NBP7 Q8NBP7 P17301 PCSK9 ITGA2 human pred
Q8NBP7 Q8NBP7 P48023 PCSK9 FASLG human pred
Q8NBP7 Q8NBP7 Q16270 PCSK9 IGFBP7 human pred
Q8NBP7 Q8NBP7 P55212 PCSK9 CASP6 human pred
Q8NBP7 Q8NBP7 Q7Z3T8 PCSK9 ZFYVE16 human pred
Q8NBP7 Q8NBP7 Q16760 PCSK9 DGKD human pred
Q8NBP7 Q8NBP7 P38646 PCSK9 HSPA9 human ortho
Q8NBP7 Q8NBP7 P46779 PCSK9 RPL28 human exp
Q8NBP7 Q8NBP7 O75369 PCSK9 FLNB human pred
Q8NBP7 Q8NBP7 Q9BUF5 PCSK9 TUBB6 human exp
Q8NBP7 Q8NBP7 P16519 PCSK9 PCSK2 human pred
Q8NBP7 Q8NBP7 Q9Y5B9 PCSK9 SUPT16H human ortho
Q8NBP7 Q8NBP7 Q9HCE7 PCSK9 SMURF1 human pred
Q8NBP7 Q8NBP7 P05106 PCSK9 ITGB3 human pred
Q8NBP7 Q8NBP7 O14944 PCSK9 EREG human pred
Q8NBP7 Q8NBP7 Q13888 PCSK9 GTF2H2 human pred
Q8NBP7 Q8NBP7 Q8WZ42 PCSK9 TTN human pred
Q8NBP7 Q8NBP7 P50897 PCSK9 PPT1 human pred
Q8NBP7 Q8NBP7 P46934 PCSK9 NEDD4 human pred
Q8NBP7 Q8NBP7 P50570 PCSK9 DNM2 human pred
Q8NBP7 Q8NBP7 Q14703 PCSK9 MBTPS1 human pred
Q8NBP7 Q8NBP7 Q8IXB1 PCSK9 DNAJC10 human exp
Q8NBP7 Q8NBP7 P29120 PCSK9 PCSK1 human pred
Q8NBP7 Q8NBP7 P28482 PCSK9 MAPK1 human ortho
Q8NBP7 Q8NBP7 P31689 PCSK9 DNAJA1 human exp
Q8NBP7 Q8NBP7 Q16595 PCSK9 FXN human pred
Q8NBP7 Q8NBP7 Q96RI1 PCSK9 NR1H4 human pred
Q8NBP7 Q8NBP7 P56199 PCSK9 ITGA1 human pred
Q8NBP7 Q8NBP7 Q63HQ2 PCSK9 EGFLAM human pred
Q8NBP7 Q8NBP7 Q00341 PCSK9 HDLBP human pred
Q8NBP7 Q8NBP7 P13667 PCSK9 PDIA4 human exp
Q8NBP7 Q8NBP7 P04792 PCSK9 HSPB1 human exp
Q8NBP7 Q8NBP7 Q8WY64 PCSK9 MYLIP human pred
Q8NBP7 Q8NBP7 P62166 PCSK9 NCS1 human ortho
Q8NBP7 Q8NBP7 P15170 PCSK9 GSPT1 human ortho
Q8NBP7 Q8NBP7 Q495A1 PCSK9 TIGIT human pred
Q8NBP7 Q8NBP7 O15116 PCSK9 LSM1 human pred
Q8NBP7 Q8NBP7 Q96EY1 PCSK9 DNAJA3 human exp,ortho
Q8NBP7 Q8NBP7 P53007 PCSK9 SLC25A1 human exp
Q8NBP7 Q8NBP7 P34932 PCSK9 HSPA4 human ortho
Q8NBP7 Q8NBP7 Q16549 PCSK9 PCSK7 human pred
Q8NBP7 Q8NBP7 O95445 PCSK9 APOM human pred
Q8NBP7 Q8NBP7 Q13490 PCSK9 BIRC2 human exp
Q8NBP7 Q8NBP7 P11021 PCSK9 HSPA5 human pred
Q8NBP7 Q8NBP7 Q12772 PCSK9 SREBF2 human pred
Q8NBP7 Q8NBP7 P0C0L5 PCSK9 C4B human pred
Q8NBP7 Q8NBP7 P78549 PCSK9 NTHL1 human pred
Q8NBP7 Q8NBP7 Q96T76 PCSK9 MMS19 human pred
Q8NBP7 Q8NBP7 P42574 PCSK9 CASP3 human pred
Q8NBP7 Q8NBP7 P07355 PCSK9 ANXA2 human exp
Q8NBP7 Q8NBP7 Q04656 PCSK9 ATP7A human pred
Q8NBP7 Q8NBP7 Q9UBN7 PCSK9 HDAC6 human pred
Q8NBP7 Q8NBP7 P29122 PCSK9 PCSK6 human pred
Q8NBP7 Q8NBP7 Q92667 PCSK9 AKAP1 human pred
Q8NBP7 Q8NBP7 O00264 PCSK9 PGRMC1 human exp
Q8NBP7 Q8NBP7 O60884 PCSK9 DNAJA2 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.