Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 8 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q8NCR3 Q8NCR3 B4DJ51 C11orf65 CALM1 human exp
Q8NCR3 Q8NCR3 Q9NPD8 C11orf65 UBE2T human exp
Q8NCR3 Q8NCR3 Q96HY3 C11orf65 CALM1 human exp
Q8NCR3 Q8NCR3 Q14847 C11orf65 LASP1 human exp
Q8NCR3 Q8NCR3 P63165 C11orf65 SUMO1 human exp
Q8NCR3 Q8NCR3 P0DP25 C11orf65 CALM3 human exp
Q8NCR3 Q8NCR3 P27482 C11orf65 CALML3 human exp
Q8NCR3 Q8NCR3 P0DP23 C11orf65 CALM1 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.