Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 29 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q8ND04 Q8ND04 Q02083 SMG8 NAAA human exp
Q8ND04 Q8ND04 Q53HC9 SMG8 EIPR1 human exp
Q8ND04 Q8ND04 Q96Q15 SMG8 SMG1 human exp
Q8ND04 Q8ND04 Q9HAU5 SMG8 UPF2 human pred
Q8ND04 Q8ND04 Q92540 SMG8 SMG7 human pred
Q8ND04 Q8ND04 Q9BRK5 SMG8 SDF4 human exp
Q8ND04 Q8ND04 Q9UPR3 SMG8 SMG5 human pred
Q8ND04 Q8ND04 Q9NPJ4 SMG8 PNRC2 human pred
Q8ND04 Q8ND04 P49746 SMG8 THBS3 human exp
Q8ND04 Q8ND04 Q9Y265 SMG8 RUVBL1 human exp
Q8ND04 Q8ND04 P15170 SMG8 GSPT1 human pred
Q8ND04 Q8ND04 O43310 SMG8 CTIF human pred
Q8ND04 Q8ND04 Q9Y5S9 SMG8 RBM8A human exp
Q8ND04 Q8ND04 O15234 SMG8 CASC3 human pred
Q8ND04 Q8ND04 Q86V87 SMG8 FAM160B2 human exp
Q8ND04 Q8ND04 Q92900 SMG8 UPF1 human exp,pred
Q8ND04 Q8ND04 Q8IX18 SMG8 DHX40 human pred
Q8ND04 Q8ND04 Q9H0W8 SMG8 SMG9 human exp
Q8ND04 Q8ND04 Q15287 SMG8 RNPS1 human pred
Q8ND04 Q8ND04 Q09161 SMG8 NCBP1 human pred
Q8ND04 Q8ND04 Q9NYA4 SMG8 MTMR4 human pred
Q8ND04 Q8ND04 P80370 SMG8 DLK1 human exp
Q8ND04 Q8ND04 Q9UJT1 SMG8 TUBD1 human pred
Q8ND04 Q8ND04 Q58A45 SMG8 PAN3 human pred
Q8ND04 Q8ND04 Q86US8 SMG8 SMG6 human pred
Q8ND04 Q8ND04 P04629 SMG8 NTRK1 human exp
Q8ND04 Q8ND04 P52298 SMG8 NCBP2 human pred
Q8ND04 Q8ND04 Q9Y3Q8 SMG8 TSC22D4 human exp
Q8ND04 Q8ND04 P60228 SMG8 EIF3E human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.