Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 11 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q8NFR7 Q8NFR7 Q9BQ70 CCDC148 TCF25 human pred
Q8NFR7 Q8NFR7 P83916 CCDC148 CBX1 human exp
Q8NFR7 Q8NFR7 Q8N6V9 CCDC148 TEX9 human exp
Q8NFR7 Q8NFR7 P17482 CCDC148 HOXB9 human pred
Q8NFR7 Q8NFR7 P02788 CCDC148 LTF human exp
Q8NFR7 Q8NFR7 Q9GZZ8 CCDC148 LACRT human exp
Q8NFR7 Q8NFR7 O75556 CCDC148 SCGB2A1 human exp
Q8NFR7 Q8NFR7 P21673 CCDC148 SAT1 human exp,pred
Q8NFR7 Q8NFR7 Q9BYD2 CCDC148 MRPL9 human pred
Q8NFR7 Q8NFR7 Q8N6Y0 CCDC148 USHBP1 human exp
Q8NFR7 Q8NFR7 O95968 CCDC148 SCGB1D1 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.