Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 24 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q8WUY3 Q8WUY3 P50993 PRUNE2 ATP1A2 human pred
Q8WUY3 Q8WUY3 Q9UBQ5 PRUNE2 EIF3K human exp
Q8WUY3 Q8WUY3 P21291 PRUNE2 CSRP1 human pred
Q8WUY3 Q8WUY3 P62854 PRUNE2 RPS26 human exp
Q8WUY3 Q8WUY3 Q96D15 PRUNE2 RCN3 human exp
Q8WUY3 Q8WUY3 P68032 PRUNE2 ACTC1 human pred
Q8WUY3 Q8WUY3 P46782 PRUNE2 RPS5 human exp
Q8WUY3 Q8WUY3 Q5SVZ6 PRUNE2 ZMYM1 human exp
Q8WUY3 Q8WUY3 Q14204 PRUNE2 DYNC1H1 human exp
Q8WUY3 Q8WUY3 P62847 PRUNE2 RPS24 human exp
Q8WUY3 Q8WUY3 P12931 PRUNE2 SRC human exp
Q8WUY3 Q8WUY3 O43237 PRUNE2 DYNC1LI2 human exp
Q8WUY3 Q8WUY3 P07948 PRUNE2 LYN human exp
Q8WUY3 Q8WUY3 P06241 PRUNE2 FYN human exp
Q8WUY3 Q8WUY3 P07947 PRUNE2 YES1 human exp
Q8WUY3 Q8WUY3 P31946 PRUNE2 YWHAB human ortho,pred
Q8WUY3 Q8WUY3 Q01844 PRUNE2 EWSR1 human exp
Q8WUY3 Q8WUY3 P10415 PRUNE2 BCL2 human pred
Q8WUY3 Q8WUY3 Q13409 PRUNE2 DYNC1I2 human exp
Q8WUY3 Q8WUY3 P08865 PRUNE2 RPSA human exp
Q8WUY3 Q8WUY3 P51693 PRUNE2 APLP1 human pred
Q8WUY3 Q8WUY3 P35749 PRUNE2 MYH11 human pred
Q8WUY3 Q8WUY3 P48539 PRUNE2 PCP4 human pred
Q8WUY3 Q8WUY3 Q9BY44 PRUNE2 EIF2A human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.