Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 9 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q8WV74 Q8WV74 Q10713 NUDT8 PMPCA human exp,ortho
Q8WV74 Q8WV74 Q96T59 NUDT8 CDRT15 human exp
Q8WV74 Q8WV74 Q8TB22 NUDT8 SPATA20 human exp
Q8WV74 Q8WV74 Q86X76 NUDT8 NIT1 human exp
Q8WV74 Q8WV74 P20155 NUDT8 SPINK2 human exp
Q8WV74 Q8WV74 A6NI79 NUDT8 CCDC69 human exp
Q8WV74 Q8WV74 Q9Y5J9 NUDT8 TIMM8B human ortho
Q8WV74 Q8WV74 P01160 NUDT8 NPPA human exp
Q8WV74 Q8WV74 Q17RF5 NUDT8 ODAPH human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.