Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 212 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q92547 Q92547 Q9UL49 TOPBP1 TCFL5 human exp
Q92547 Q92547 P26358 TOPBP1 DNMT1 human pred
Q92547 Q92547 P35249 TOPBP1 RFC4 human pred
Q92547 Q92547 Q14691 TOPBP1 GINS1 human exp,pred
Q92547 Q92547 Q96IZ0 TOPBP1 PAWR human pred
Q92547 Q92547 P0CG48 TOPBP1 UBC human exp
Q92547 Q92547 P03372 TOPBP1 ESR1 human exp
Q92547 Q92547 Q7L590 TOPBP1 MCM10 human pred
Q92547 Q92547 P61077 TOPBP1 UBE2D3 human pred
Q92547 Q92547 Q02880 TOPBP1 TOP2B human exp,pred
Q92547 Q92547 Q14188 TOPBP1 TFDP2 human pred
Q92547 Q92547 P61758 TOPBP1 VBP1 human pred
Q92547 Q92547 Q00987 TOPBP1 MDM2 human exp
Q92547 Q92547 P07900 TOPBP1 HSP90AA1 human pred
Q92547 Q92547 P52701 TOPBP1 MSH6 human exp,pred
Q92547 Q92547 Q9Y4A5 TOPBP1 TRRAP human pred
Q92547 Q92547 Q9Y4B6 TOPBP1 VPRBP human exp
Q92547 Q92547 P42345 TOPBP1 MTOR human pred
Q92547 Q92547 P18074 TOPBP1 ERCC2 human exp
Q92547 Q92547 Q14676 TOPBP1 MDC1 human exp,pred
Q92547 Q92547 O75928 TOPBP1 PIAS2 human exp,pred
Q92547 Q92547 Q9BXW9 TOPBP1 FANCD2 human pred
Q92547 Q92547 Q7Z569 TOPBP1 BRAP human pred
Q92547 Q92547 P01106 TOPBP1 MYC human pred
Q92547 Q92547 O95229 TOPBP1 ZWINT human pred
Q92547 Q92547 P33993 TOPBP1 MCM7 human pred
Q92547 Q92547 O95985 TOPBP1 TOP3B human pred
Q92547 Q92547 Q96QT4 TOPBP1 TRPM7 human ortho
Q92547 Q92547 P07992 TOPBP1 ERCC1 human exp
Q92547 Q92547 Q9NTJ3 TOPBP1 SMC4 human exp,pred
Q92547 Q92547 Q9NZJ0 TOPBP1 DTL human pred
Q92547 Q92547 P78527 TOPBP1 PRKDC human pred
Q92547 Q92547 P27694 TOPBP1 RPA1 human exp,pred
Q92547 Q92547 Q9UGU0 TOPBP1 TCF20 human pred
Q92547 Q92547 P24941 TOPBP1 CDK2 human pred
Q92547 Q92547 Q03169 TOPBP1 TNFAIP2 human exp
Q92547 Q92547 P35251 TOPBP1 RFC1 human pred
Q92547 Q92547 P24864 TOPBP1 CCNE1 human pred
Q92547 Q92547 Q13416 TOPBP1 ORC2 human pred
Q92547 Q92547 P67870 TOPBP1 CSNK2B human pred
Q92547 Q92547 Q96AY2 TOPBP1 EME1 human pred
Q92547 Q92547 Q15398 TOPBP1 DLGAP5 human pred
Q92547 Q92547 P43246 TOPBP1 MSH2 human pred
Q92547 Q92547 P54274 TOPBP1 TERF1 human pred
Q92547 Q92547 Q13415 TOPBP1 ORC1 human pred
Q92547 Q92547 O75943 TOPBP1 RAD17 human pred
Q92547 Q92547 O60671 TOPBP1 RAD1 human pred
Q92547 Q92547 Q9BSD3 TOPBP1 RHNO1 human exp
Q92547 Q92547 O15151 TOPBP1 MDM4 human pred
Q92547 Q92547 P40937 TOPBP1 RFC5 human pred
Q92547 Q92547 P35250 TOPBP1 RFC2 human pred
Q92547 Q92547 Q9NPI1 TOPBP1 BRD7 human pred
Q92547 Q92547 Q9BX63 TOPBP1 BRIP1 human exp,pred
Q92547 Q92547 Q9UKT4 TOPBP1 FBXO5 human pred
Q92547 Q92547 P39748 TOPBP1 FEN1 human pred
Q92547 Q92547 P46736 TOPBP1 BRCC3 human pred
Q92547 Q92547 Q13315 TOPBP1 ATM human exp,pred
Q92547 Q92547 O95071 TOPBP1 UBR5 human exp
Q92547 Q92547 Q9NVI1 TOPBP1 FANCI human pred
Q92547 Q92547 Q14191 TOPBP1 WRN human pred
Q92547 Q92547 Q05048 TOPBP1 CSTF1 human pred
Q92547 Q92547 P06748 TOPBP1 NPM1 human pred
Q92547 Q92547 P11142 TOPBP1 HSPA8 human exp
Q92547 Q92547 P49841 TOPBP1 GSK3B human pred
Q92547 Q92547 Q12778 TOPBP1 FOXO1 human pred
Q92547 Q92547 Q99728 TOPBP1 BARD1 human exp,pred
Q92547 Q92547 P12004 TOPBP1 PCNA human exp,pred
Q92547 Q92547 Q9H6Z9 TOPBP1 EGLN3 human exp
Q92547 Q92547 Q92830 TOPBP1 KAT2A human pred
Q92547 Q92547 P31749 TOPBP1 AKT1 human exp,pred
Q92547 Q92547 Q00526 TOPBP1 CDK3 human pred
Q92547 Q92547 P11021 TOPBP1 HSPA5 human exp
Q92547 Q92547 P30291 TOPBP1 WEE1 human pred
Q92547 Q92547 O60921 TOPBP1 HUS1 human pred
Q92547 Q92547 Q8WXE1 TOPBP1 ATRIP human exp,ortho,pred
Q92547 Q92547 P14635 TOPBP1 CCNB1 human pred
Q92547 Q92547 O60934 TOPBP1 NBN human exp,pred
Q92547 Q92547 Q7Z2Z1 TOPBP1 TICRR human exp
Q92547 Q92547 O94985 TOPBP1 CLSTN1 human exp
Q92547 Q92547 Q6PCD5 TOPBP1 RFWD3 human pred
Q92547 Q92547 P49736 TOPBP1 MCM2 human pred
Q92547 Q92547 Q99638 TOPBP1 RAD9A human exp,pred
Q92547 Q92547 P49959 TOPBP1 MRE11 human pred
Q92547 Q92547 O14867 TOPBP1 BACH1 human exp
Q92547 Q92547 Q14686 TOPBP1 NCOA6 human pred
Q92547 Q92547 Q16576 TOPBP1 RBBP7 human pred
Q92547 Q92547 P11388 TOPBP1 TOP2A human pred
Q92547 Q92547 P67809 TOPBP1 YBX1 human pred
Q92547 Q92547 P78396 TOPBP1 CCNA1 human pred
Q92547 Q92547 A4D177 TOPBP1 - human pred
Q92547 Q92547 P23025 TOPBP1 XPA human pred
Q92547 Q92547 Q08211 TOPBP1 DHX9 human pred
Q92547 Q92547 P09874 TOPBP1 PARP1 human pred
Q92547 Q92547 Q92547 TOPBP1 TOPBP1 human exp
Q92547 Q92547 Q92878 TOPBP1 RAD50 human exp,pred
Q92547 Q92547 Q13547 TOPBP1 HDAC1 human pred
Q92547 Q92547 P51587 TOPBP1 BRCA2 human pred
Q92547 Q92547 P18846 TOPBP1 ATF1 human pred
Q92547 Q92547 P54132 TOPBP1 BLM human exp,pred
Q92547 Q92547 Q8NG50 TOPBP1 RDM1 human pred
Q92547 Q92547 O95347 TOPBP1 SMC2 human pred
Q92547 Q92547 P36873 TOPBP1 PPP1CC human exp,pred
Q92547 Q92547 O14776 TOPBP1 TCERG1 human pred
Q92547 Q92547 Q9H9A7 TOPBP1 RMI1 human exp
Q92547 Q92547 Q92793 TOPBP1 CREBBP human pred
Q92547 Q92547 O60343 TOPBP1 TBC1D4 human exp
Q92547 Q92547 P29590 TOPBP1 PML human exp
Q92547 Q92547 P33240 TOPBP1 CSTF2 human pred
Q92547 Q92547 P41279 TOPBP1 MAP3K8 human pred
Q92547 Q92547 Q8TEA8 TOPBP1 DTD1 human exp
Q92547 Q92547 P09001 TOPBP1 MRPL3 human pred
Q92547 Q92547 P25789 TOPBP1 PSMA4 human pred
Q92547 Q92547 Q9H8V3 TOPBP1 ECT2 human pred
Q92547 Q92547 P98170 TOPBP1 XIAP human pred
Q92547 Q92547 P11387 TOPBP1 TOP1 human exp
Q92547 Q92547 Q9HAW4 TOPBP1 CLSPN human pred
Q92547 Q92547 Q8IY92 TOPBP1 SLX4 human exp
Q92547 Q92547 Q15645 TOPBP1 TRIP13 human pred
Q92547 Q92547 P40938 TOPBP1 RFC3 human pred
Q92547 Q92547 Q86XI2 TOPBP1 NCAPG2 human pred
Q92547 Q92547 Q6ZW49 TOPBP1 PAXIP1 human pred
Q92547 Q92547 P54278 TOPBP1 PMS2 human exp
Q92547 Q92547 Q12888 TOPBP1 TP53BP1 human exp,pred
Q92547 Q92547 Q8NHY5 TOPBP1 HUS1B human pred
Q92547 Q92547 P38398 TOPBP1 BRCA1 human exp,pred
Q92547 Q92547 P46527 TOPBP1 CDKN1B human pred
Q92547 Q92547 Q8NEM0 TOPBP1 MCPH1 human pred
Q92547 Q92547 Q13105 TOPBP1 ZBTB17 human exp,pred
Q92547 Q92547 P51532 TOPBP1 SMARCA4 human exp,pred
Q92547 Q92547 Q8IXW5 TOPBP1 RPAP2 human exp
Q92547 Q92547 Q13257 TOPBP1 MAD2L1 human pred
Q92547 Q92547 O75419 TOPBP1 CDC45 human exp,pred
Q92547 Q92547 Q06609 TOPBP1 RAD51 human pred
Q92547 Q92547 P62805 TOPBP1 HIST1H4A human exp
Q92547 Q92547 Q9NXR7 TOPBP1 BRE human pred
Q92547 Q92547 P40692 TOPBP1 MLH1 human pred
Q92547 Q92547 Q9H4L7 TOPBP1 SMARCAD1 human exp
Q92547 Q92547 O00311 TOPBP1 CDC7 human pred
Q92547 Q92547 Q01094 TOPBP1 E2F1 human exp,ortho,pred
Q92547 Q92547 Q9UBU7 TOPBP1 DBF4 human pred
Q92547 Q92547 Q14186 TOPBP1 TFDP1 human pred
Q92547 Q92547 O76064 TOPBP1 RNF8 human pred
Q92547 Q92547 Q9NW38 TOPBP1 FANCL human pred
Q92547 Q92547 P63261 TOPBP1 ACTG1 human exp
Q92547 Q92547 Q92769 TOPBP1 HDAC2 human pred
Q92547 Q92547 O14777 TOPBP1 NDC80 human pred
Q92547 Q92547 Q9NS87 TOPBP1 KIF15 human pred
Q92547 Q92547 P22626 TOPBP1 HNRNPA2B1 human pred
Q92547 Q92547 Q9H0H5 TOPBP1 RACGAP1 human pred
Q92547 Q92547 Q9Y5N6 TOPBP1 ORC6 human pred
Q92547 Q92547 Q9BQI6 TOPBP1 SLF1 human pred
Q92547 Q92547 Q14201 TOPBP1 BTG3 human pred
Q92547 Q92547 Q13309 TOPBP1 SKP2 human pred
Q92547 Q92547 Q14680 TOPBP1 MELK human pred
Q92547 Q92547 P06400 TOPBP1 RB1 human pred
Q92547 Q92547 P53350 TOPBP1 PLK1 human exp
Q92547 Q92547 P63165 TOPBP1 SUMO1 human pred
Q92547 Q92547 Q9UPV0 TOPBP1 CEP164 human pred
Q92547 Q92547 P10275 TOPBP1 AR human pred
Q92547 Q92547 P52292 TOPBP1 KPNA2 human pred
Q92547 Q92547 Q16531 TOPBP1 DDB1 human exp
Q92547 Q92547 P20226 TOPBP1 TBP human pred
Q92547 Q92547 Q9NRL2 TOPBP1 BAZ1A human pred
Q92547 Q92547 Q8N2W9 TOPBP1 PIAS4 human pred
Q92547 Q92547 P35659 TOPBP1 DEK human pred
Q92547 Q92547 Q92922 TOPBP1 SMARCC1 human pred
Q92547 Q92547 O96017 TOPBP1 CHEK2 human pred
Q92547 Q92547 Q9NP87 TOPBP1 POLM human pred
Q92547 Q92547 Q96B01 TOPBP1 - human pred
Q92547 Q92547 P04637 TOPBP1 TP53 human pred
Q92547 Q92547 P52732 TOPBP1 KIF11 human pred
Q92547 Q92547 P62807 TOPBP1 HIST1H2BC human exp
Q92547 Q92547 P16104 TOPBP1 H2AFX human ortho,pred
Q92547 Q92547 Q07864 TOPBP1 POLE human exp
Q92547 Q92547 P49760 TOPBP1 CLK2 human exp
Q92547 Q92547 Q15554 TOPBP1 TERF2 human pred
Q92547 Q92547 P00519 TOPBP1 ABL1 human exp,pred
Q92547 Q92547 O15360 TOPBP1 FANCA human pred
Q92547 Q92547 Q16254 TOPBP1 E2F4 human pred
Q92547 Q92547 Q15648 TOPBP1 MED1 human pred
Q92547 Q92547 O95758 TOPBP1 PTBP3 human exp
Q92547 Q92547 Q9BZS1 TOPBP1 FOXP3 human ortho
Q92547 Q92547 P24752 TOPBP1 ACAT1 human exp
Q92547 Q92547 P06493 TOPBP1 CDK1 human pred
Q92547 Q92547 O60566 TOPBP1 BUB1B human pred
Q92547 Q92547 O60216 TOPBP1 RAD21 human pred
Q92547 Q92547 P08047 TOPBP1 SP1 human pred
Q92547 Q92547 Q99708 TOPBP1 RBBP8 human pred
Q92547 Q92547 Q01664 TOPBP1 TFAP4 human exp
Q92547 Q92547 Q9UQE7 TOPBP1 SMC3 human pred
Q92547 Q92547 P28749 TOPBP1 RBL1 human pred
Q92547 Q92547 O14746 TOPBP1 TERT human pred
Q92547 Q92547 P18146 TOPBP1 EGR1 human pred
Q92547 Q92547 O14980 TOPBP1 XPO1 human pred
Q92547 Q92547 O94782 TOPBP1 USP1 human pred
Q92547 Q92547 P25205 TOPBP1 MCM3 human pred
Q92547 Q92547 P13010 TOPBP1 XRCC5 human pred
Q92547 Q92547 Q92560 TOPBP1 BAP1 human pred
Q92547 Q92547 O75925 TOPBP1 PIAS1 human pred
Q92547 Q92547 Q92466 TOPBP1 DDB2 human pred
Q92547 Q92547 Q13535 TOPBP1 ATR human exp,pred
Q92547 Q92547 Q13185 TOPBP1 CBX3 human pred
Q92547 Q92547 P42224 TOPBP1 STAT1 human pred
Q92547 Q92547 P32780 TOPBP1 GTF2H1 human pred
Q92547 Q92547 O14757 TOPBP1 CHEK1 human exp,pred
Q92547 Q92547 Q14566 TOPBP1 MCM6 human pred
Q92547 Q92547 Q13873 TOPBP1 BMPR2 human exp,ortho,pred
Q92547 Q92547 Q99986 TOPBP1 VRK1 human pred
Q92547 Q92547 Q00341 TOPBP1 HDLBP human exp
Q92547 Q92547 P20248 TOPBP1 CCNA2 human pred
Q92547 Q92547 Q01831 TOPBP1 XPC human pred
Q92547 Q92547 P49321 TOPBP1 NASP human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.