Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 12 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q969W1 Q969W1 Q38SD2 ZDHHC16 LRRK1 human pred
Q969W1 Q969W1 P48039 ZDHHC16 MTNR1A human exp
Q969W1 Q969W1 P42684 ZDHHC16 ABL2 human pred
Q969W1 Q969W1 P00519 ZDHHC16 ABL1 human exp
Q969W1 Q969W1 Q4KMG0 ZDHHC16 CDON human pred
Q969W1 Q969W1 O43900 ZDHHC16 PRICKLE3 human pred
Q969W1 Q969W1 Q9Y4G6 ZDHHC16 TLN2 human pred
Q969W1 Q969W1 Q96IW2 ZDHHC16 SHD human pred
Q969W1 Q969W1 O75751 ZDHHC16 SLC22A3 human pred
Q969W1 Q969W1 Q9Y3L3 ZDHHC16 SH3BP1 human pred
Q969W1 Q969W1 Q06187 ZDHHC16 BTK human pred
Q969W1 Q969W1 P07203 ZDHHC16 GPX1 human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.