Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 13 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q96M32 Q96M32 Q02413 AK7 DSG1 human pred
Q96M32 Q96M32 Q9H3R2 AK7 MUC13 human exp
Q96M32 Q96M32 P23109 AK7 AMPD1 human pred
Q96M32 Q96M32 P55263 AK7 ADK human pred
Q96M32 Q96M32 Q9P286 AK7 PAK5 human pred
Q96M32 Q96M32 Q9Y5L0 AK7 TNPO3 human exp
Q96M32 Q96M32 P00492 AK7 HPRT1 human pred
Q96M32 Q96M32 Q01432 AK7 AMPD3 human pred
Q96M32 Q96M32 P21589 AK7 NT5E human pred
Q96M32 Q96M32 P27707 AK7 DCK human pred
Q96M32 Q96M32 P49961 AK7 ENTPD1 human pred
Q96M32 Q96M32 Q6PJT7 AK7 ZC3H14 human exp
Q96M32 Q96M32 Q92917 AK7 GPKOW human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.