Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 7 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q9BSG1 Q9BSG1 P23771 ZNF2 GATA3 human pred
Q9BSG1 Q9BSG1 Q13263 ZNF2 TRIM28 human exp,ortho,pred
Q9BSG1 Q9BSG1 O14744 ZNF2 PRMT5 human exp
Q9BSG1 Q9BSG1 P30281 ZNF2 CCND3 human exp
Q9BSG1 Q9BSG1 P05067 ZNF2 APP human exp
Q9BSG1 Q9BSG1 Q9BZW7 ZNF2 TSGA10 human exp
Q9BSG1 Q9BSG1 P60409 ZNF2 KRTAP10-7 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.