Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 14 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q9BUA3 Q9BUA3 P00533 C11orf84 EGFR human exp
Q9BUA3 Q9BUA3 Q5TC82 C11orf84 RC3H1 human exp
Q9BUA3 Q9BUA3 P68431 C11orf84 HIST1H3A human exp
Q9BUA3 Q9BUA3 Q9P2P5 C11orf84 HECW2 human exp
Q9BUA3 Q9BUA3 P62258 C11orf84 YWHAE human exp
Q9BUA3 Q9BUA3 Q9UKB1 C11orf84 FBXW11 human exp
Q9BUA3 Q9BUA3 Q9BPZ2 C11orf84 SPIN2B human exp
Q9BUA3 Q9BUA3 Q96Q27 C11orf84 ASB2 human exp
Q9BUA3 Q9BUA3 P62993 C11orf84 GRB2 human exp
Q9BUA3 Q9BUA3 Q5JUX0 C11orf84 SPIN3 human exp
Q9BUA3 Q9BUA3 Q9H2C0 C11orf84 GAN human exp
Q9BUA3 Q9BUA3 P32121 C11orf84 ARRB2 human exp
Q9BUA3 Q9BUA3 Q9Y657 C11orf84 SPIN1 human exp
Q9BUA3 Q9BUA3 P11441 C11orf84 UBL4A human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.