Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 20 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q9BYJ4 Q9BYJ4 Q6ZMJ2 TRIM34 SCARA5 human pred
Q9BYJ4 Q9BYJ4 O75604 TRIM34 USP2 human exp
Q9BYJ4 Q9BYJ4 Q8IYM9 TRIM34 TRIM22 human pred
Q9BYJ4 Q9BYJ4 Q9BYJ4 TRIM34 TRIM34 human exp
Q9BYJ4 Q9BYJ4 P12757 TRIM34 SKIL human pred
Q9BYJ4 Q9BYJ4 Q8IX30 TRIM34 SCUBE3 human pred
Q9BYJ4 Q9BYJ4 Q5VVX9 TRIM34 UBE2U human exp
Q9BYJ4 Q9BYJ4 Q9C035 TRIM34 TRIM5 human exp,pred
Q9BYJ4 Q9BYJ4 P51948 TRIM34 MNAT1 human exp
Q9BYJ4 Q9BYJ4 P14373 TRIM34 TRIM27 human pred
Q9BYJ4 Q9BYJ4 P12755 TRIM34 SKI human pred
Q9BYJ4 Q9BYJ4 P61086 TRIM34 UBE2K human exp
Q9BYJ4 Q9BYJ4 Q13490 TRIM34 BIRC2 human exp
Q9BYJ4 Q9BYJ4 Q6ZMU5 TRIM34 TRIM72 human pred
Q9BYJ4 Q9BYJ4 Q9C037 TRIM34 TRIM4 human pred
Q9BYJ4 Q9BYJ4 Q12933 TRIM34 TRAF2 human pred
Q9BYJ4 Q9BYJ4 Q13064 TRIM34 MKRN3 human exp
Q9BYJ4 Q9BYJ4 P19474 TRIM34 TRIM21 human pred
Q9BYJ4 Q9BYJ4 A6NLU0 TRIM34 RFPL4A human pred
Q9BYJ4 Q9BYJ4 Q9C030 TRIM34 TRIM6 human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.